Myxoma of the renal sinus: case report and literature review
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Date
2012
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Abstract
Miksoma nadir görülen benign mezankimal tümör olup literatürde sıklıkla kalp ve deride rapor edilmiştir. Böbrekte görülen mezankimal tümörler içerisinde miksoma oldukça nadir izlenmekte olup literatürde bugüne kadar 11 olgu bildirilmiştir. Bunlardan bir tanesi renal sinüs yerleşimlidir. 82 yaşında erkek hasta, parsiyel üriner obstrüksiyon semptomlarıyla hastanemize kabul edildi. Yapılan abdominal bilgisayarlı tomografide sol böbrek hilusunda yerleşim gösteren hipodens, parankimle sınırları net olarak seçilemeyen, 9 cm boyutunda solid kitle tespit edildi. Böbrekte kitle nedeniyle sol renal nefrektomi yapılan hastanın gross incelemesinde, renal sinüs kaynaklı sınırları net olarak seçilemeyen jelatinöz görünümde tümör dokusu izlendi. Mikroskopik olarak bol mukoid materyal içerisinde dağılmış, iğsi sitoplazmalı, bazıları yıldızsı görünümde hücrelerden oluştuğu gözlendi. Tümör hücreleri vimentin ile pozitif, düz kas aktini ile fokal pozitiflik gösterirken, S-100 protein, epitelyal membran antijeni ve pansitokeratin ile negatif boyanma göstermiştir. Biz burada renal sinüs kaynaklı ikinci olguyu sunduk.
Myxoma is a rare mesenchymal tumor and it is mainly seen in heart and skin. Renal myxoma is extremely rare. To date, eleven cases of kidney myxomas have been reported in the literature. One of them is myxoma of the renal sinus. Our case was an 82-year-old man admitted to our hospital symptoms related to the urinary tract obstruction. Abdominal computerized tomography revealed a solid, hypodense mass 9 cm in diameter infiltrating the renal parenchyma in the renal pelvis. The patient underwent nephrectomy. The resected kidney contained gelatinous tumor with indistinct borders. The tumor was composed of slender, bland, spindle-shaped cells with large amounts of mucoid material. Tumor cells were positively stained with vimentin, focally stained positive for smooth muscle actin and had negative reactivity for S-100 protein, epithelial membrane antigen and pancytokeratin. Herein we report the second case of renal myxoma arising from the renal sinus.
Myxoma is a rare mesenchymal tumor and it is mainly seen in heart and skin. Renal myxoma is extremely rare. To date, eleven cases of kidney myxomas have been reported in the literature. One of them is myxoma of the renal sinus. Our case was an 82-year-old man admitted to our hospital symptoms related to the urinary tract obstruction. Abdominal computerized tomography revealed a solid, hypodense mass 9 cm in diameter infiltrating the renal parenchyma in the renal pelvis. The patient underwent nephrectomy. The resected kidney contained gelatinous tumor with indistinct borders. The tumor was composed of slender, bland, spindle-shaped cells with large amounts of mucoid material. Tumor cells were positively stained with vimentin, focally stained positive for smooth muscle actin and had negative reactivity for S-100 protein, epithelial membrane antigen and pancytokeratin. Herein we report the second case of renal myxoma arising from the renal sinus.
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Türk Patoloji Dergisi
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Volume
28
Issue
1
