Digital clubbing may be an indicator of systemic atherosclerosis even at microvascular level

dc.contributor.authorHelvacı, Mehmet Rami
dc.contributor.authorAydın, Leyla Yılmaz
dc.contributor.authorAydın, Yusuf
dc.date.accessioned2020-05-01T09:11:26Z
dc.date.available2020-05-01T09:11:26Z
dc.date.issued2012
dc.departmentDÜ, Tıp Fakültesi, Dahili Tıp Bilimleri Bölümüen_US
dc.descriptionWOS: 000314345000014en_US
dc.description.abstractBackground: Presence of any relationship between digital clubbing and microvascular atherosclerosis was tried to be understood. Methods: Cases with digital clubbing and controls were studied. Results: The study included 104 cases with clubbing and 120 controls. Mean age of clubbing cases was 49.2 years, and there was a male predominance (81.7%) among them. There were significantly higher prevalences of smoking and chronic obstructive pulmonary disease (COPD) in the clubbing group (69.2 versus 41.6% and 27.8 versus 10.8%, respectively, p<0.001 for both). Although body mass index (BMI), weight, and fasting plasma glucose (FPG) were lower in the clubbing group, the differences were nonsignificant probably due to the small sample sizes. Although the negative effect of small sample sizes, prevalence of type 2 diabetes mellitus (DM) and mean value of systolic blood pressure (BP) were significanlty lower in the clubbing group (12.5 versus 21.6% and 127.6 versus 136.9 mmHg, respectively, p<0.05 for both). On the other hand, prevalence of coronary heart disease (CHD) and/or peripheric artery disease (PAD) were significantly higher in the clubbing group (7.6 versus 0.0%, p<0.01). Conclusions: There are significant relationships between digital clubbing and smoking, COPD, and CHD and/or PAD probably due to strong atherosclerotic effects of smoking with highly suspected atherosclerotic background of COPD. Whereas the BMI, weight, FPG, systolic BP, and prevalence of DM are inversely related with digital clubbing probably due to suppressor effects of smoking on appetite. So clubbing may be a significant indicator of systemic atherosclerosis even at microvascular level.en_US
dc.identifier.endpage3981en_US
dc.identifier.issn1840-2291
dc.identifier.issn1986-8103
dc.identifier.issue12en_US
dc.identifier.scopusqualityN/Aen_US
dc.identifier.startpage3977en_US
dc.identifier.urihttps://hdl.handle.net/20.500.12684/5585
dc.identifier.volume6en_US
dc.identifier.wosqualityN/Aen_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.language.isoenen_US
dc.publisherDrunpp-Sarajevoen_US
dc.relation.ispartofHealthmeden_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectClubbingen_US
dc.subjectatherosclerosisen_US
dc.subjectsmokingen_US
dc.titleDigital clubbing may be an indicator of systemic atherosclerosis even at microvascular levelen_US
dc.typeArticleen_US

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