Myalgia Frequency in Patients with COVID-19 and Its Relationship with Creatine Kinase Levels
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Tarih
2020
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info:eu-repo/semantics/openAccess
Özet
Aim: Many studies have showed that myalgia is a common onset symptom in coronavirusdisease 2019 (COVID-19). This study aimed to determine the frequency of muscle pain inpatients followed with COVID-19 diagnosis, and to investigate the relationship betweenmuscle pain and creatine kinase (CK), pH, lactate and lactate dehydrogenase (LDH) levels.Material and Methods: One hundred ten patients diagnosed with COVID-19 in our hospitalwere included retrospectively in this study. Presence of myalgia at the time of admission andon the 14th day of control were investigated. The first admission laboratory findings, 3rd dayCK values and 14th day control CK values of all patients were recorded retrospectively fromtheir files.Results: The study included 110 patients diagnosed with COVID-19. Fifty patients (45.5%)had muscle pain at the time of admission, and it was one of the most common musculoskeletalcomplaints. High CK results were obtained in 48 (43.6%) of the 110 patients at the time ofadmission. Thirty-two (66.7%) of 48 patients with high CK had muscle pain (p<0.001). In thepatients with muscle pain, the CK levels observed on 1st, 3rd, and 14th day of the disease werefound to be significantly higher than in those without muscle pain (p<0.001, p=0.003,p=0.029). No significant relationship was found between complaints of muscle pain andlactate, pH, and LDH values.Conclusion: Since some patients may only present with musculoskeletal symptoms such asmyalgia, it is important that clinicians consider COVID-19 in patients presenting with myalgiaand high CK levels.
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Cilt
22
Sayı
S1
