Effect of Bacterial Nanocellulose and Plant-Containing Facial Serum on Hyperpigmentation in in-vitro Conditions
Küçük Resim Yok
Tarih
2024
Dergi Başlığı
Dergi ISSN
Cilt Başlığı
Yayıncı
North Carolina State Univ Dept Wood & Paper Sci
Erişim Hakkı
info:eu-repo/semantics/openAccess
Özet
This study investigated the effect of some herbal extracts, such as licorice root, white mulberry leaf, green tea leaf, and grape seed, with a combination of bacterial nanocellulose and some bioactive materials, such as ascorbic acid, niacinamide, hexylresorcinol, and alpha-arbutin, on treatment of hyperpigmentation. The effect of the prepared emulsions on hyperpigmentation was revealed by analyzing their tyrosinase inhibition properties, their ability to stop melanin production, or their properties of whitening the brown spot on the skin. In addition to the physicochemical properties of the 5 different emulsions obtained, tyrosinase, collagenase, and elastase enzyme activities, antioxidant properties, cytotoxicity, and microbiological analyzes were performed by cell-culture modelling. Finally, a dermocosmetic facial serum was designed that is compatible with skin pH, is homogeneously mixed, has good spreading properties, does not cause any microbiological growth, does not inhibit elastase activity while stimulating collagenase activity, reduces melanin production by inhibiting the tyrosinase enzyme, and does not have any toxic effects.
Açıklama
Anahtar Kelimeler
Whitening bio-compounds, Bacterial nanocellulose, Tyrosinase inhibitors, Hyperpigmentation, Herbal extracts, Spreading Properties, Skin, Tyrosinase, Hydroquinone, Emollients, Products, Extracts, Acid, Tea
Kaynak
Bioresources
WoS Q Değeri
N/A
Scopus Q Değeri
Q3
Cilt
19
Sayı
2