Serum Clara cell secretory protein (CC-16) in non-smoking patients with obstructive sleep apnea

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dc.contributor.authorBalbay, Ege Güleç
dc.contributor.authorAtaoğlu, Özlem
dc.contributor.authorErçelik, Merve
dc.contributor.authorŞahin, İbrahim Ethem
dc.contributor.authorAdmış, Özlem
dc.contributor.authorArbak, Peri Meram
dc.date.accessioned2020-04-30T13:33:21Z
dc.date.available2020-04-30T13:33:21Z
dc.date.issued2020
dc.departmentDÜ, Tıp Fakültesi, Dahili Tıp Bilimleri Bölümüen_US
dc.descriptionPubMed ID: 32144590en_US
dc.description.abstractObjective: This study aimed to determine the association between the severity of obstructive sleep apnea (OSA) and serum Clara cell protein (CC16) levels in non-smoking patients with OSA. Methods: This prospective study included non-smoking patients who presented with sleep-related disturbances and underwent polysomnography (PSG). The serum CC16 level was measured and its relationship to PSG parameters was investigated. Results: The study included 128 patients (83 men) with a mean age of 48.4 ± 11.9. OSA was detected in 66 men (70%) and 29 women (30%) (p = 0.051). The severity of OSA was mild in 32 (25%), moderate in 28 (22%), and severe in 35 (27%) of the patients. There was no significant difference in CC16 levels between the OSA group (1746 ± 1006) and the OSA negative group (1721 ± 1201, p = 0.91) levels. There was no significant difference between the CC16 levels of the each four groups. Mean serum CC16 levels were significantly lower in OSA negative men than OSA positive men (777 vs 1462, p = 0.005). No significant difference was observed in CC16 values according to OSA severity in women. Conclusion: The serum CC16 level does not differ between non-smoking OSA patients and OSA negative patients. © 2020, Springer Nature Switzerland AG.en_US
dc.identifier.doi10.1007/s11325-020-02042-zen_US
dc.identifier.issn1520-9512
dc.identifier.scopusqualityN/Aen_US
dc.identifier.urihttps://dx.doi.org/10.1007/s11325-020-02042-z
dc.identifier.urihttps://hdl.handle.net/20.500.12684/617
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoenen_US
dc.publisherSpringeren_US
dc.relation.ispartofSleep and Breathingen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectClara cell protein; Obstructive sleep apnea syndromeen_US
dc.titleSerum Clara cell secretory protein (CC-16) in non-smoking patients with obstructive sleep apneaen_US
dc.typeArticleen_US

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