Investigation of tribological properties of HEMA-based cryogels as potential articular cartilage biomaterials

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dc.authoridAkıncıoğlu, Gülşah/0000-0002-4768-4935
dc.authoridSarkaya, Koray/0000-0003-0177-5134
dc.authorwosidAkıncıoğlu, Gülşah/F-6826-2017
dc.contributor.authorSarkaya, Koray
dc.contributor.authorAkıncıoğlu, Gülşah
dc.contributor.authorAkıncıoğlu, Sıtkı
dc.date.accessioned2023-07-26T11:54:51Z
dc.date.available2023-07-26T11:54:51Z
dc.date.issued2022
dc.departmentDÜ, Gümüşova Meslek Yüksekokulu, Makine ve Metal Teknolojileri Bölümüen_US
dc.description.abstractTribology is one of the most important issues for the repair and regeneration of living tissues in the human body, as it deals with the wear, lubrication, and friction of interrelated surfaces. Hydrogels show potential as cartilage regeneration agents due to their biocompatibility and behave similarly to the lubricating mechanisms found in cartilage tissue. Cryogels, which are included in the class of hydrogels, are more stable than hydrogels in terms of mechanical strength, and references to the tribological properties of these polymers in the literature have been minimal so far. In this study, poly(HEMA-N-vinyl formamide) (poly(HEMA-NVF) and poly(HEMA-N-vinylpyrrolidone) (poly(HEMA-NVP) cryogels with improved hydrophilic properties were synthesized with pure poly(HEMA) cryogel. The swelling properties of HEMA-based cryogels were examined under the heading of various parameters, and their physicochemical characterizations were characterized via FTIR, SEM, mercury intrusion porosimetry, elemental analysis (EDX), and TGA methods. Before investigating tribological properties, a cytotoxicity test was performed for all cryogels. Then, in line with the study's primary purpose, the tribological properties of cryogels were examined. Abrasion tests were carried out on a pin-on-disc tester linked with ASTM G99-05 standard. According to the results, the friction coefficient of poly(HEMA-NVF) and poly(HEMA-NVP) cryogels is 21.62% and 10.51% higher than poly(HEMA) cryogel, respectively. In addition, the results of abrasion and 3D surface topography images prove that the poly(HEMA-NVP) cryogel wears less and its surface is less deformed than other cryogels.en_US
dc.identifier.doi10.1080/25740881.2022.2039190
dc.identifier.endpage1190en_US
dc.identifier.issn2574-0881
dc.identifier.issn2574-089X
dc.identifier.issue11en_US
dc.identifier.scopus2-s2.0-85126134417en_US
dc.identifier.scopusqualityQ2en_US
dc.identifier.startpage1174en_US
dc.identifier.urihttps://doi.org/10.1080/25740881.2022.2039190
dc.identifier.urihttps://hdl.handle.net/20.500.12684/12939
dc.identifier.volume61en_US
dc.identifier.wosWOS:000765613400001en_US
dc.identifier.wosqualityQ3en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.institutionauthorAkıncıoğlu, Gülşah
dc.institutionauthorAkıncıoğlu, Sıtkı
dc.language.isoenen_US
dc.publisherTaylor & Francis Incen_US
dc.relation.ispartofPolymer-Plastics Technology and Materialsen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.snmz$2023V1Guncelleme$en_US
dc.subjectCryogel; Friction Coefficient; Wear Rate; Wear Resistanceen_US
dc.subjectMesenchymal Stem-Cells; Gelatin Cryogels; Hydrogels; Behavior; Protein; Gels; Chondrogenesis; Constructs; Scaffolds; Densityen_US
dc.titleInvestigation of tribological properties of HEMA-based cryogels as potential articular cartilage biomaterialsen_US
dc.typeArticleen_US

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