The Effect of Epinephrine Administration on Return of Spontaneous Circulation and One-Month Mortality with Cardiopulmonary Arrest Patients

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dc.authorid
dc.contributor.authorSabak, Mustafa
dc.contributor.authorAl, Behçet
dc.contributor.authorOktay, Mehmet Murat
dc.contributor.authorZengin, Suat
dc.contributor.authorBoğan, Mustafa
dc.contributor.authorGümüşboğa, Hasan
dc.contributor.authorKazaz, Tanyeli Güneyligil
dc.date.accessioned2021-12-01T18:23:52Z
dc.date.available2021-12-01T18:23:52Z
dc.date.issued2020
dc.department[Belirlenecek]en_US
dc.description.abstractObjective: The objective of this study is to determine the effect of epinephrine administration on the return of spontaneous circulation (ROSC) and one-month mortality in patients with cardiopulmonary arrest.Methods: We conducted this study between August 1, 2016 and May 31, 2017. Importantly, we included the witnessed cases (?18years) of in-emergency department cardiopulmonary arrest (IEDCA) and out-of-hospital cardiopulmonary arrest (OHCA) in thestudy. We divided the patients into two groups: the adrenaline group (Group 1) and the non-adrenaline group (Group 2). Thereafter, we investigated ROSC and one-month mortality in them.Results: We included 183 patients (50.3% of males and 49.7% of females with a mean age of 64.2±16.8 years) in the study. Thepercentages of IEDCA and OHCA cases were 25.1% and 74.9%, respectively. Epinephrine was administered to 100 (54.6%) patients(Group 1). Among these patients, 15.9% (n=29) of the patients had shockable rhythms (ventricular fibrillation, pulseless ventriculartachycardia) and 84.1% (n=154) of them had non-shockable rhythms (asystole, pulseless electrical activity) as the initial rhythm.ROSC and one-month mortality rate of these patients were 24% (n=44) and 72.8% (n=36), respectively. The one-month mortalityrates of Group 1 (30% of patients had IEDCA and 70% of patients had OHCA) and Group 2 were 43.8% and 56.2%, respectively(p=0.0231). The ROSC and one-month mortality rates of Group 1 and Group 2 cases, whose initial rhythm was a shockable rhythm,were 26.6% and 50% vs. 42.8% and 66.6%, respectively.Conclusion: In this study, we found no significant difference in terms of obtaining ROSC between the shockable rhythm and ROSCin the IEDCA and OHCA cases (p=0.963 and p=0.141, respectively). The effect of epinephrine administration on patients with IEDCA and OHCA whose ROSC was obtained on one-month mortality was not statistically significant (p>0.05).en_US
dc.identifier.doi10.5152/eurjther.2020.19124
dc.identifier.endpage191en_US
dc.identifier.issn2564-7784
dc.identifier.issn2564-7040
dc.identifier.issue3en_US
dc.identifier.startpage183en_US
dc.identifier.urihttps://doi.org/10.5152/eurjther.2020.19124
dc.identifier.urihttps://app.trdizin.gov.tr/makale/TXpjNU1ETXpNdz09
dc.identifier.urihttps://hdl.handle.net/20.500.12684/9790
dc.identifier.volume26en_US
dc.identifier.wosWOS:000574459200005en_US
dc.identifier.wosqualityN/Aen_US
dc.indekslendigikaynakTR-Dizinen_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.language.isoenen_US
dc.relation.ispartofEuropean Journal of Therapeuticsen_US
dc.relation.publicationcategoryMakale - Ulusal Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.subject[No Keywords]en_US
dc.titleThe Effect of Epinephrine Administration on Return of Spontaneous Circulation and One-Month Mortality with Cardiopulmonary Arrest Patientsen_US
dc.typeArticleen_US

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