Associations of glycated hemoglobin (HbA1c) level with central corneal and macular thickness in diabetic patients without macular edema
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Tarih
2018
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Erişim Hakkı
info:eu-repo/semantics/openAccess
Özet
Objectives: To determine the correlation between central corneal thickness (CCT) and central macularthickness (CMT), and fasting plasma glucose levels and HbA1c levels before diabetic macular edema (DME)in type 2 diabetes mellitus (DM) patients without diabetic retinopathy.Methods: Forty-four eyes of subjects diagnosed with type 2 DM, and 45 healthy control subjects participatedin this study. Detailed ophthalmologic examination was performed with all participants. CMT was measuredin both groups by Spectral-domain optical coherence tomography. CCT measurements were made with anEchoscan US-500 ultrasonic pachymeter. Blood biochemical tests for glycated hemoglobin (HbA1c) and fastingplasma glucose levels were run on all patients.Results: The results of the study showed that the mean CCT was significantly thicker in type 2 DM patients563.84 33.25 ?m than in the controls 550.13 28.41 ?m (p 0.039). The mean of CMT was 231.27 37.74?m in the study group and 225.38 38.33 ?m in the control group (p 0.05). No relationship was foundbetween CCT and CMT and HbA1c level in the study and control groups.Conclusions: The mean CCT was significantly thicker in type 2 DM patients without diabetic retinopathy thanin the controls. The mean CMT is thicker in type 2 DM patients without diabetic retinopathy patients than inthe controls, but this difference was not statistically significant. Optical coherence tomography can be a perfectdetector for early detection of DME.
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Anahtar Kelimeler
Acil Tıp, Adli Tıp, Alerji, Anatomi ve Morfoloji, Androloji, Anestezi, Biyofizik, Biyokimya ve Moleküler Biyoloji, Biyoloji, Biyoteknoloji ve Uygulamalı Mikrobiyoloji, Cerrahi, Dermatoloji, Endokrinoloji ve Metabolizma, Enfeksiyon Hastalıkları, Fizyoloji, Gastroenteroloji ve Hepatoloji, Genel ve Dahili Tıp, Geriatri ve Gerontoloji, Göz Hastalıkları, Halk ve Çevre Sağlığı, Hematoloji, Hücre Biyolojisi, İmmünoloji, Kadın Hastalıkları ve Doğum, Kalp ve Kalp Damar Sistemi, Klinik Nöroloji, Kulak, Burun, Boğaz, Mikrobiyoloji, Nörolojik Bilimler, Odyoloji ve Konuşma-Dil Patolojisi, Onkoloji, Ortopedi, Patoloji, Pediatri, Periferik Damar Hastalıkları, Psikiyatri, Radyoloji, Nükleer Tıp, Tıbbi Görüntüleme, Rehabilitasyon, Romatoloji, Sağlık Bilimleri ve Hizmetleri, Solunum Sistemi, Spor Bilimleri, Tamamlayıcı ve Entegre Tıp, Temel Sağlık Hizmetleri, Tıbbi Araştırmalar Deneysel, Tıbbi Etik, Tıbbi İnformatik, Tıbbi Laboratuar Teknolojisi, Transplantasyon, Tropik Tıp, Üroloji ve Nefroloji, Yoğun Bakım, Tıp
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4
