Investigation of chemical content and antimicrobial activities of different plant sources of anatolian propolis samples

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dc.authorscopusid55843638600en_US
dc.contributor.authorSönmez, E.
dc.date.accessioned2024-08-23T16:07:28Z
dc.date.available2024-08-23T16:07:28Z
dc.date.issued2023en_US
dc.departmentDüzce Üniversitesien_US
dc.description.abstractThe ethnopharmacological approach combined with chemical and biological methods can be a useful model in the field of pharmacology. One of these approaches, apitherapy, is the use of bee and hive products for therapeutic purposes. Propolis is among the best known of these bee products. The chemical composition of propolis varies according to the local or endemic flora, bee species, geographical origin and season. This study is to determine the antimicrobial activity differences between chestnut and polyfloral origin propolis against various pathogenic bacterial species. First of all, the Liquid Chromatography-Mass Spectrometry (LC-MS/MS) method was used for the determination of bioactive components known to be responsible for antimicrobial activity. Folin-Ciocalteu method and colorimetric aluminum chloride assay were used to determine the total phenolic (TP) and flavonoid (TF) amounts. 19 different pathogenic microorganisms were selected to test the antimicrobial activity levels of propolis samples with agar well diffusion and minimum inhibitory concentration (MIC) methods. TP and TF values of chestnut propolis (71.06 mg GAE/mL-11.75 mg QE/mL) were significantly higher than polyfloral sample (36.84 mg GAE/mL-7.04 mg QE/mL). Chrysin, a flavone derivative, was the most abundant compound in both samples. The MIC values of chestnut propolis ranged from 19.5 to 2500 µg/mL, while the MIC value of polyfloral origin propolis was between 39.06 and 5000 µg/mL. The most susceptible strain was Mycobacterium smegmatis for both samples with different concentration. Notably, it was observed that the botanical origins affect the chemical composition of propolis, and this situation can also be effect antibacterial and antifungal activity in respective propolis because of the different amount and diversity of bioactive compounds. Consequently, chestnut propolis is a promising candidate for drug discovery that can be used to treat some infectious diseases, including diseases related with resistant bacteria. © 2023 Authors. All rights reserved.en_US
dc.identifier.doi10.31467/uluaricilik.1208667
dc.identifier.endpage48en_US
dc.identifier.issn1303-0248
dc.identifier.issue1en_US
dc.identifier.scopus2-s2.0-85168332996en_US
dc.identifier.scopusqualityQ4en_US
dc.identifier.startpage37en_US
dc.identifier.trdizinid1207704en_US
dc.identifier.urihttps://doi.org/10.31467/uluaricilik.1208667
dc.identifier.urihttps://search.trdizin.gov.tr/tr/yayin/detay/1207704
dc.identifier.urihttps://hdl.handle.net/20.500.12684/14660
dc.identifier.volume23en_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakTR-Dizinen_US
dc.institutionauthorSönmez, E.en_US
dc.language.isoenen_US
dc.publisherBursa Uludag Universityen_US
dc.relation.ispartofUludag Aricilik Dergisien_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.subjectantifungal activityen_US
dc.subjectantimicrobialen_US
dc.subjectChestnut propolisen_US
dc.subjectflavonoiden_US
dc.subjectphenolic compositionen_US
dc.subjecttotal phenolicen_US
dc.titleInvestigation of chemical content and antimicrobial activities of different plant sources of anatolian propolis samplesen_US
dc.title.alternativeFarklı Bitki Kaynaklı Anadolu Propolis Örneklerinin Kimyasal İçeriği ve Antimikrobial Aktivitelerinin Araştırılmasıen_US
dc.typeArticleen_US

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