The Impact of Plasma Glucose Levels on In-Hospital and Long-Term Mortality in Non-Diabetic Patients with ST-Segment Elevation Myocardial Infarction Patients

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dc.contributor.authorTatlısu, Mustafa Adem
dc.contributor.authorKaya, Adnan
dc.contributor.authorKeskin, Muhammed
dc.contributor.authorBaycan, Ömer Faruk
dc.contributor.authorKayapınar, Osman
dc.contributor.authorÇalışkan, Mustafa
dc.date.accessioned2020-04-30T23:33:48Z
dc.date.available2020-04-30T23:33:48Z
dc.date.issued2020
dc.departmentDÜ, Tıp Fakültesi, Dahili Tıp Bilimleri Bölümüen_US
dc.description.abstractObjective: Increased admission plasma glucose can be seen in the acute phase of acute coronary syndromes (ACS). Hence, we performed a retrospective study to evaluate the admission plasma glucose concentration in patients with ST-segment elevation myocardial infarction (STEMI) undergoing primary percutaneous coronary intervention (pPCI) and who had no previous diagnosis of Diabetes Mellitus (DM). Methods: This retrospective study included 2504 consecutive confirmed STEMI patients treated with pPCI. The patients were divided into quantiles according to the admission glucose levels. Quantile I: 94 +/- 7 mg/dL (n = 626), quantile II: 112 +/- 5 mg/dL (n = 626), quantile III: 131 +/- 6 mg/dL (n = 626), quantile IV: 184 +/- 46 mg/dL (n = 626). Results: Patients with higher plasma glucose (Q4) had 6.6 times higher in-hospital all-cause mortality rates (95% CI: 3.95-9.30) and 3.12 times higher (95% CI: 2.2-4.4) long-term all-cause mortality rates than patients with lower plasma glucose (Q1-Q3), who had lower rates and were used as the reference. This significant relationship remained even after adjustment for all confounders. Conclusions: Even though glucose-lowering therapy is recommended in ACS patients with glucose levels >180 mg/dL, our results showed that high plasma glucose, even lower than 180 mg/dL, could predict in-hospital and long-term mortality.en_US
dc.identifier.endpage60en_US
dc.identifier.issn1309-3878
dc.identifier.issue1en_US
dc.identifier.startpage55en_US
dc.identifier.urihttps://hdl.handle.net/20.500.12684/5045
dc.identifier.volume12en_US
dc.identifier.wosWOS:000518456300010en_US
dc.identifier.wosqualityN/Aen_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.language.isoenen_US
dc.publisherDuzce Univen_US
dc.relation.ispartofKonuralp Tıp Dergisi
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectHyperglycemiaen_US
dc.subjectLong-Term Mortalityen_US
dc.subjectST-Segment Elevation Myocardial Infactionen_US
dc.titleThe Impact of Plasma Glucose Levels on In-Hospital and Long-Term Mortality in Non-Diabetic Patients with ST-Segment Elevation Myocardial Infarction Patientsen_US
dc.typeArticleen_US

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