CAN WE USE THE TRIGLYCERIDE/HDL RATIO TO DETERMINE INSULIN RESISTANCE IN OBESITY SCREENING AND FOLLOW-UP IN PRIMARY CARE?

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dc.authorscopusid37005547200
dc.authorscopusid57191259441
dc.authorscopusid56901954900
dc.authorscopusid57222485759
dc.authorscopusid57479166800
dc.contributor.authorGamsızkan, Zerrin
dc.contributor.authorÖnmez, Attila
dc.contributor.authorŞahin, İ.E.
dc.contributor.authorErdemir, G.
dc.contributor.authorÜnal, S.
dc.date.accessioned2023-07-26T11:54:04Z
dc.date.available2023-07-26T11:54:04Z
dc.date.issued2022
dc.departmentDÜ, Tıp Fakültesi, Cerrahi Tıp Bilimleri Bölümü, Aile Hekimliği Ana Bilim Dalıen_US
dc.description.abstractObjectives: Obese patients are followed up with periodic laboratory tests. Insulin resistance is also a parameter used in these tests. There is a need for parameters that can determine insulin resistance more easily and practically. The aim of our study is to investigate the discriminative power of triglyceride (Tg) and triglyceride/high-density lipoprotein cholesterol ratio (Tg/HDL) for Homeostatic Model Assessment for Insulin Resistance (HOMA-IR) in our patient population by examining the laboratory findings. Materials and Methods: In this retrospective study, the laboratory data of patients who applied to the Family Medicine Obesity Polyclinic of Düzce University Hospital between April 2018 and April 2019 with the desire to lose weight and/or have healthy lifestyle suggestions were examined. Results: Of the 512 patients included in our study, 66.40% (n=340) were female and 33.59% (n=172) were male. In the examination performed on patients grouped according to their Body Mass Index (BMI), Total cholesterol, HDL, Low-density lipoprotein (LDL), Tg, HOMA-IR, Insulin and Tg/HDL ratios were significantly different between the groups. The cut-off value in the ROC analysis of the Tg/HDL parameter between patients with and without insulin resistance was found to be 2.29 with 66% sensitivity and 55% specificity (AUC: 0.634, p<0.001). In Spearman's correlation analysis of Tg/HDL and HOMA-IR, both parameters were found to have a statistically significant correlation (r: 0.248; p< 0.000). Conclusion: The significant relationship between the high Tg/HDL ratio and HOMA-IR detected in the results of our study shows that the Tg/HDL ratio can be used as a practical tool to evaluate insulin resistance in obese patients. © 2022 Universidade Estadual de Mato Grosso do Sul. All Rights Reserved.en_US
dc.identifier.doi10.5505/amj.2022.38991
dc.identifier.endpage459en_US
dc.identifier.issn1303-2283
dc.identifier.issue3en_US
dc.identifier.scopus2-s2.0-85140996941en_US
dc.identifier.scopusqualityQ4en_US
dc.identifier.startpage451en_US
dc.identifier.trdizinid1128783en_US
dc.identifier.urihttps://doi.org/10.5505/amj.2022.38991
dc.identifier.urihttps://search.trdizin.gov.tr/yayin/detay/1128783
dc.identifier.urihttps://hdl.handle.net/20.500.12684/12715
dc.identifier.volume22en_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakTR-Dizinen_US
dc.institutionauthorGamsızkan, Zerrin
dc.institutionauthorÖnmez, Attila
dc.institutionauthorŞahin, İ.E.
dc.institutionauthorErdemir, G.
dc.institutionauthorÜnal, S.
dc.language.isoenen_US
dc.publisherAnkara Yıldırım Beyazit Universityen_US
dc.relation.ispartofAnkara Medical Journalen_US
dc.relation.publicationcategoryKonferans Öğesi - Uluslararası - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.snmz$2023V1Guncelleme$en_US
dc.subjectHOMA-IRen_US
dc.subjectinsulin resistanceen_US
dc.subjectObesityen_US
dc.subjectTg/HDLen_US
dc.titleCAN WE USE THE TRIGLYCERIDE/HDL RATIO TO DETERMINE INSULIN RESISTANCE IN OBESITY SCREENING AND FOLLOW-UP IN PRIMARY CARE?en_US
dc.typeConference Objecten_US

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