The Role of the Urine Dipstick Test in the Detection of Abnormal Proteinuria Using Different Cut-off Levels in Hypertensive Pregnancies

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dc.contributor.authorCetin, Caglar
dc.contributor.authorHalici, Belfin Nur Arici
dc.contributor.authorKütük, Mehmet Serdar
dc.contributor.authorTakmaz, Taha
dc.contributor.authorToprak, Ali
dc.contributor.authorGorchiyeva, Irana
dc.date.accessioned2023-04-10T20:20:58Z
dc.date.available2023-04-10T20:20:58Z
dc.date.issued2022
dc.departmentRektörlük, Rektörlüğe Bağlı Birimler, Düzce Üniversitesi Dergilerien_US
dc.description.abstractAim: The aim of this study was to determine the diagnostic accuracy of different urine dipstick protein threshold levels in predicting the presence of abnormal proteinuria in pregnant women with hypertension.Material and Methods: A total of 326 singleton pregnant women who underwent 501 urine protein tests and who had suspected preeclampsia were included in this retrospective study. Patient data was taken including medical and obstetric history. The results of dipstick urinalysis and concurrent 24-hour urine protein excretion measurements were compared to determine the accuracy of urinalysis.Results: A dipstick result of 1+ was found to be the best cut-off to predict 500 mg of protein excretion per day, with sensitivity and specificity of 62.09% and 88.97%, respectively. A 2+ proteinuria dipstick cut-off had high specificity and positive predictive value (PPV) (99.05% and 98.84%, respectively) for the prediction of 300 mg of protein excretion per day; this cut-off had low sensitivity (21.46%). A cut-off of 1+ also provided satisfactory specificity and PPV (91.43% and 94.48%, respectively) for the detection of 300 mg of protein excretion per day, but sensitivity was compromised (38.89%). Among 301 patients with negative dipstick results, 212 had a 24-hour urine protein extraction greater than 300 mg, with a false negative rate of 70.43%.Conclusion: The results suggest that the urine protein dipstick measurement has limited quantitative ability for the prediction of abnormal proteinuria. Additionally, the use of 500 mg 24-hours protein excretion as a cut-off value for abnormal proteinuria may provide useful data.en_US
dc.identifier.doi10.18678/dtfd.939565
dc.identifier.endpage11en_US
dc.identifier.issn1307-671X
dc.identifier.issue1en_US
dc.identifier.startpage7en_US
dc.identifier.trdizinid1070934en_US
dc.identifier.urihttp://doi.org/10.18678/dtfd.939565
dc.identifier.urihttps://search.trdizin.gov.tr/yayin/detay/1070934
dc.identifier.urihttps://hdl.handle.net/20.500.12684/11499
dc.identifier.volume24en_US
dc.indekslendigikaynakTR-Dizinen_US
dc.language.isoenen_US
dc.relation.ispartofDüzce Tıp Fakültesi Dergisien_US
dc.relation.publicationcategoryMakale - Ulusal Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.subjectpregnancyen_US
dc.subjectproteinuriaen_US
dc.subjectdipstick urinalysisen_US
dc.subjectpreeclampsiaen_US
dc.subject24-hour urine proteinen_US
dc.titleThe Role of the Urine Dipstick Test in the Detection of Abnormal Proteinuria Using Different Cut-off Levels in Hypertensive Pregnanciesen_US
dc.typeArticleen_US

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