The Relationship of Thyroid Hormone Levels and Motor Symptoms in Parkinson's Disease

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dc.contributor.authorŞahin, Erkan Melih
dc.contributor.authorÇam, Mustafa
dc.contributor.authorOcak, Özgül
dc.date.accessioned2023-04-10T20:20:59Z
dc.date.available2023-04-10T20:20:59Z
dc.date.issued2022
dc.departmentRektörlük, Rektörlüğe Bağlı Birimler, Düzce Üniversitesi Dergilerien_US
dc.description.abstractAim: This study aimed to investigate the relationship between thyroid hormone levels and the motor symptoms of Parkinson's patients. Material and Methods: Neurology clinic logs of the patients diagnosed with Parkinson's disease and whose thyroid function tests were measured between 01.01.2018 and 01.04.2021 were selected. Those with primary thyroid hormone disorder were excluded. Motor symptom stages were determined according to the modified Hoehn and Yahr scale (mHYS) by records. According to the thyroid function test results, whether there was a difference in motor symptoms, duration of the disease, and effects of the drugs were examined. Results: Of the 93 patients included in the study, 53 (57.0%) were male and 40 (43.0%) were female. The median age of the patients was 71 years. The motor symptoms of the patients were classified as stage 1 in 21 (22.6%), stage 1.5 in 18 (19.4%), stage 2 in 29 (31.2%), stage 2.5 in 13 (14.0%), stage 3 in 4 (4.3%), stage 4 in 6 (6.5%), and stage 5 in 2 (2.2%) patients. The median levels of TSH, fT3, and fT4 were 2.075 uIU/ml, 2.925 ng/dl, and 1.235 ng/dl, respectively. There was no significant correlation between the mHYS stages of the patients and TSH (r=-0.148, p=0.164), fT3 (r=-0.073, p=0.623), and fT4 levels (r=0.075, p=0.491). Conclusion: There was no relationship between the severity of motor symptoms and hormone levels in patients with normal thyroid functions. Thyroid dysfunction may mimic many motor findings, but they do not affect the severity of motor findings in Parkinson's patients.en_US
dc.identifier.doi10.18678/dtfd.1068664
dc.identifier.endpage146en_US
dc.identifier.issn1307-671X
dc.identifier.issue2en_US
dc.identifier.startpage142en_US
dc.identifier.trdizinid1115669en_US
dc.identifier.urihttp://doi.org/10.18678/dtfd.1068664
dc.identifier.urihttps://search.trdizin.gov.tr/yayin/detay/1115669
dc.identifier.urihttps://hdl.handle.net/20.500.12684/11509
dc.identifier.volume24en_US
dc.indekslendigikaynakTR-Dizinen_US
dc.language.isoenen_US
dc.relation.ispartofDüzce Tıp Fakültesi Dergisi
dc.relation.publicationcategoryMakale - Ulusal Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.subjectParkinson's diseaseen_US
dc.subjectmotor symptomsen_US
dc.subjectThyroid functionsen_US
dc.titleThe Relationship of Thyroid Hormone Levels and Motor Symptoms in Parkinson's Diseaseen_US
dc.typeArticleen_US

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