The Diagnostic and Prognostic Importance of Neurological Findings on SARS-CoV-2 Infection

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2020

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info:eu-repo/semantics/openAccess

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The coronavirus invades the nervous system with the spread we call neuroinvasion, and"cytokine storm" becomes an important factor affecting the course of the disease. Seriousdamage occurs in the brain and other organs as a result of cytokine storm. Evidence isaccumulating that the coronavirus, which infects millions of people all over the world, affectsboth the central and peripheral nervous system and muscles as well as the respiratory tract.Increasing evidence has revealed neurological involvement in 36-54% of the patients, whichcorresponds to almost one in every 2 or 3 patients. In severe acute respiratory syndromecoronavirus 2 (SARS-CoV-2) patients, we frequently encounter neurological symptoms suchas smell and taste disturbances, fatigue and muscle pain, headache, nausea, vomiting, impairedconsciousness, numbness in hands and feet. To a lesser extent, we encounter neurologicalhandicaps such as dizziness, inflammation of the meninges, loss of myelin in nerve tissue,muscle inflammation, and severe rhabdomyolysis. Some of the nervous system diseasesaccompanying SARS-CoV-2 disease recover with complete or partial sequelae. Observationof permanent dysfunction in patients with neurological findings draws attention to theimportance of a detailed neurological evaluation in the examination of these cases.

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22

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S1

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