Investigation of structural, spectroscopic, dielectric, magnetic, and in vitro biocompatibility properties of Sr/Ni co-doped hydroxyapatites

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dc.authoridAteş, Tankut/0000-0002-4519-2953
dc.authoridKaygılı, Ömer/0000-0002-2321-1455
dc.authoridFlemban, Tahani/0000-0002-2661-5092
dc.authoridDemirci, Tuna/0000-0001-8933-4944
dc.authorwosidAteş, Tankut/AAK-2168-2020
dc.authorwosidKaygılı, Ömer/A-4801-2017
dc.authorwosidFlemban, Tahani/G-5057-2018
dc.contributor.authorErcan, Filiz
dc.contributor.authorKayed, Tarek S.
dc.contributor.authorKaygılı, Ömer
dc.contributor.authorBulut, Niyazi
dc.contributor.authorAlmohazey, Dana
dc.contributor.authorAteş, Tankut
dc.contributor.authorAl-Ahmari, Fatimah Saad
dc.date.accessioned2023-07-26T11:50:28Z
dc.date.available2023-07-26T11:50:28Z
dc.date.issued2022
dc.departmentDÜ, Mühendislik Fakültesi, Elektrik-Elektronik Mühendisliği Bölümüen_US
dc.description.abstractIn this study, the changes caused by Ni and Sr additives on the structural, thermal, dielectric, and magnetic properties of hydroxyapatite (HAp) samples were examined and reported for the first time in detail. Some effects of the Sr/Ni site disorder on the crystallographic, dielectric, and magnetic properties in Sr/Ni-HAp have been examined, as well as their cytotoxicity effects. The addition of Ni affected the morphology of nanoparticles with a low agglomeration increase. Our results showed that the dielectric constant (epsilon') and dielectric loss (epsilon '') have greater values at low frequencies than at higher frequencies for all the samples. It can be concluded that Ni and Sr additions to the HAp structure contribute to the development of thermal, magnetic, and dielectric properties required to mimic natural HAp in the study conducted with the idea of creating a medical application area for bone healing and regeneration. The cytotoxicity test of the produced nanoparticles and the evaluation of the results were also performed using human foreskin fibroblasts (HFF). The viability of cells after treatment for 48 h ranged between 50 and 75%. While 0.37Ni-0.37Sr-HAp and 1.11Ni-0.37Sr-HAp were similar to 0.37Sr-HAp, 0.74Ni-0.37Sr-HAp had the highest cellular viability. At 0.1 mg/mL, 0.74Ni-0.37Sr-HAp had a viability of 79.97% compared to the untreated control cells. Our Sr/Ni-HAp nanoparticles have promising medical applications in bone healing and regeneration.en_US
dc.description.sponsorshipDeanship of Scientific Research of Imam Abdulrahman Bin Faisal University [2020-135-BASRC]en_US
dc.description.sponsorshipThe authors acknowledge the financial support provided by the Deanship of Scientific Research of Imam Abdulrahman Bin Faisal University (Project No: 2020-135-BASRC). Also, the authors acknowledge the facilities used at Basic and Applied Scientific Research Center (BASRC) and Science College, at Imam Abdulrahman Bin Faisal University.en_US
dc.identifier.doi10.1016/j.ceramint.2022.05.354
dc.identifier.endpage26607en_US
dc.identifier.issn0272-8842
dc.identifier.issn1873-3956
dc.identifier.issue18en_US
dc.identifier.scopus2-s2.0-85131450339en_US
dc.identifier.scopusqualityQ1en_US
dc.identifier.startpage26585en_US
dc.identifier.urihttps://doi.org/10.1016/j.ceramint.2022.05.354
dc.identifier.urihttps://hdl.handle.net/20.500.12684/12353
dc.identifier.volume48en_US
dc.identifier.wosWOS:000873316800004en_US
dc.identifier.wosqualityQ1en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.institutionauthorErcan, İsmail
dc.language.isoenen_US
dc.publisherElsevier Sci Ltden_US
dc.relation.ispartofCeramics Internationalen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.snmz$2023V1Guncelleme$en_US
dc.subjectAtomic And Molecular Structure; Hydroxyapatites; Magnetic Properties; Dielectric Propertiesen_US
dc.subjectMicrostructural Properties; Calcium Hydroxyapatites; Crystal-Structure; Phosphate; Proliferation; Conductivity; Cytotoxicity; Substitution; Composites; Mechanismsen_US
dc.titleInvestigation of structural, spectroscopic, dielectric, magnetic, and in vitro biocompatibility properties of Sr/Ni co-doped hydroxyapatitesen_US
dc.typeArticleen_US

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