The treatment of genital lichen sclerosus with pimecrolimus 1%: Case report [Pimekrolimus %1 krem ile genital liken sklerozusun tedavisi]
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Date
2011
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info:eu-repo/semantics/closedAccess
Abstract
Lichen sclerosus (LS) is inflammatory disorder of unknown etiology that affects pati ents 6 months of age to late adulthood. It usually affects anogenital region. The lesions are generally asymptomatic, but may cause discomfort with itching and pain. LS is uncommon in childhood, and it is more common among girls. In children, the disorder may be confused with changes seen in sexual abuse, leading to delay in appropriate diagnosis. The use of topical steroids is very effec tive the management of anogenital LS. But topical corticosteroids may causes skin atrophy, telangiectasia especially when treating atrophy prone sites such as anogenital region. Because of that, safer therapeutic options are required, especially in the treatment of children. The efficacy of topical calcineurin inhibitors has been demonstrated for genital LS recently. Here, we present a case of a 7 year old girl with genital lichen sclerosus who showed great clinical and subjective improvement with pimecrolimus cream. Copyright © 2011 by Türkiye Klinikleri.
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Keywords
Calcineurin; Pimecrolimus; Vulvar lichen sclerosus
Journal or Series
Turkiye Klinikleri Dermatoloji
WoS Q Value
Scopus Q Value
Q4
Volume
21
Issue
2
