Early Stage Muscarinic Findings and Syndromic Classification in Wild Mushroom Poisoning

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dc.contributor.authorYılmaz, Hakan
dc.contributor.authorKazbek, Baturay Kansu
dc.contributor.authorKaya, Ertuğrul
dc.contributor.authorAkata, Ilgaz
dc.contributor.authorKöksoy, Ülkü Ceren
dc.contributor.authorTüzüner, Filiz
dc.date.accessioned2020-05-01T09:11:33Z
dc.date.available2020-05-01T09:11:33Z
dc.date.issued2018
dc.departmentDÜ, Tıp Fakültesi, Dahili Tıp Bilimleri Bölümüen_US
dc.descriptionAkata, Ilgaz/0000-0002-1731-1302en_US
dc.descriptionWOS: 000452006700006en_US
dc.description.abstractMushroom poisoning is a frequently encountered health problem around the globe. Depending on its type and toxin, it results in a wide spectrum of issues that range from asymptomatic findings to fatal organ failure. Since the toxin of the mushroom leading to poisoning is often unidentified, syndromic classification may benefit clinical management according to the findings of target organ system toxicity. A 64-year-old female patient with comorbidities such as diabetes mellitus, coronary artery disease, hypertension and hyperlipidemia was admitted to the intensive care unit. Approximately four hours after consuming wild mushrooms the patient's diarrhea, muscle cramps, cold sweating, blurry vision, coughing and shortness of breath complaints have been begun. Her respiratory system examination revealed tachypnea, generalized bilateral rhonchus, bronchorrhea and wheezing. Patient was normotensive and had bradycardia (heart rate 35 beats/minute). She had anxiety and the Glasgow Coma score was 15. Her pupillary bilateral isochoric, miotic and light reflexes were diminished. In her arterial blood gas pH level 7.26, partial carbon dioxide pressure: 34 mmHg, potassium: 5.3 mmol/L, sodium: 130 mmol/L, lactate: 5.3 mmol/L, bicarbonate: 16 mEq/L and base excess: -10,3 mmol/L was found. Target organ system toxicity findings and timing of occurrence indicated early-onset cholinergic syndrome. Treatments that consisted of intravenous atropine, fluid, electrolytes and sodium bicarbonate alleviated the toxicity in a short period of time. Late mycologic examination results that followed the treatment revealed that the patient was poisoned by Inocybe lacera, a mushroom type that contains muscarine. With this case presentation, we summarized the syndromic classification that we use in the clinical management in the light of current information in the literature.en_US
dc.identifier.doi10.4274/tybd.08379en_US
dc.identifier.endpage121en_US
dc.identifier.issn2602-2974
dc.identifier.issue3en_US
dc.identifier.startpage115en_US
dc.identifier.urihttps://doi.org/10.4274/tybd.08379
dc.identifier.urihttps://hdl.handle.net/20.500.12684/5653
dc.identifier.volume16en_US
dc.identifier.wosqualityN/Aen_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.language.isotren_US
dc.publisherGalenos Yayinciliken_US
dc.relation.ispartofTurkish Journal Of Intensive Care-Turk Yogun Bakim Dergisien_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.subjectMushroom poisoningen_US
dc.subjectsyndromic classificationen_US
dc.subjectmuscarinen_US
dc.subjectInocybe laceraen_US
dc.titleEarly Stage Muscarinic Findings and Syndromic Classification in Wild Mushroom Poisoningen_US
dc.typeArticleen_US

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