INVESTIGATION OF CAUSATIVE AGENTS IN COMMUNITY-ACQUIRED ATYPICAL PNEUMONIA CASES

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dc.contributor.authorÇalışkan, Emel
dc.contributor.authorÖksüz, Şükrü
dc.contributor.authorÖztürk, Cihadiye Elif
dc.contributor.authorŞahin, İdris
dc.contributor.authorKılınçel, Özge
dc.contributor.authorAkar, Nida
dc.contributor.authorAlaşan, Fatif
dc.date.accessioned2020-04-30T23:18:36Z
dc.date.available2020-04-30T23:18:36Z
dc.date.issued2019
dc.departmentDÜ, Tıp Fakültesi, Temel Tıp Bilimleri Bölümüen_US
dc.descriptionWOS: 000471836900038en_US
dc.description.abstractTo investigate the causative agents involved in atypical community-acquired pneumonia (CAP) patients with lower respiratory tract infections. This prospective study (October 2014-August 2016) included 92 adult patients with pre-existing CAP. Serum samples were analyzed for IgG and IgM antibodies using the indirect immunofluorescence antibody (IFA) method. Causative agents associated with typical pneumonia were evaluated in simultaneously obtained sputum cultures. The IgM antibodies and/or the cultures of typical agents exhibited positivity for atypical CAP causative agents in 26 (28%) of the patients. Positive IgM antibodies were found for influenza B virus in five patients, parainfluenza serotype 2 virus in four, echovirus in four, parainfluenza serotype 1 virus in two, parainfluenza serotype 3 virus in two, influenza A (H1N1) virus in two, C. pneumoniae in two and H. influenzae in one. Thirteen (50%) of these patients had typical bacterial growth, while more than one agent was detected in five (20%). The rate of atypical causative agents other than L. pneumophila was quite high. Viruses were the main agents in the atypical CAP patients. The high incidence of typical pneumonia agents found in these patients indicates the necessity of determining the etiologic agents prior to initiation of treatment.en_US
dc.description.sponsorshipDuzce University Medical Faculty Scientific Research Projects (DUBAP) [2014/53]en_US
dc.description.sponsorshipThe study was supported by the Duzce University Medical Faculty Scientific Research Projects (DUBAP) and was approved by the Duzce University Faculty of Medicine Ethics Committee (No. 2014/53).en_US
dc.identifier.endpage3932en_US
dc.identifier.issn1018-4619
dc.identifier.issn1610-2304
dc.identifier.issue5en_US
dc.identifier.startpage3928en_US
dc.identifier.urihttps://hdl.handle.net/20.500.12684/3428
dc.identifier.volume28en_US
dc.identifier.wosWOS:000471836900038en_US
dc.identifier.wosqualityQ4en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.language.isoenen_US
dc.publisherParlar Scientific Publications (P S P)en_US
dc.relation.ispartofFresenius Environmental Bulletinen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectAtypical pneumoniaen_US
dc.subjectindirect immunofluorescence antibodyen_US
dc.subjectinfluenza virusen_US
dc.subjectelderly patienten_US
dc.titleINVESTIGATION OF CAUSATIVE AGENTS IN COMMUNITY-ACQUIRED ATYPICAL PNEUMONIA CASESen_US
dc.typeArticleen_US

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