Changes in Bone Mineral Density after Kidney Transplantation
Yükleniyor...
Dosyalar
Tarih
2020
Yazarlar
Dergi Başlığı
Dergi ISSN
Cilt Başlığı
Yayıncı
Erişim Hakkı
info:eu-repo/semantics/openAccess
Özet
Aim: The aim of this study was to evaluate changes in lumbar and femoral bone mineraldensity (BMD) in the post-transplant period.Material and Methods: A total of 69 consecutive adult (>18 years of age) patients whounderwent kidney transplantation between Jan 2016 and Jul 2019 were included in thisretrospective study. The demographic features and laboratory findings of the patients (serumcorrected calcium, phosphorus, alkaline phosphatase, creatinine, eGFR, i-parathormone and25(OH) D vitamin levels) were recorded. BMD was evaluated by dual energy X-rayabsorptiometry (DEXA).Results: According to the DEXA results, lumbar and femoral T scores were -1.1±1.3and -1.1±1.1, respectively. Lumbar assessment revealed osteoporosis in 12 (17.4%) patientsand osteopenia in 24 (34.8%) patients. Femoral assessment revealed osteoporosis in 7 (10.1%)patients and osteopenia in 29 (42.0%) patients. The first year, 1-2 year and >2 years follow updata revealed osteoporosis in 4.3%, 5.8% and 7.2% of patients in the lumbar region and in2.9%, 2.9% and 4.3% of patients in the femoral region, respectively. There was no significantdifference in cumulative steroid dose between patients with BMD loss in the lumbar (p=0.197)and femoral (p=0.971) region and patients with normal BMD measurement. In addition, nosignificant relation was observed between the induction therapy and loss of BMD in the lumbarregion (p=0.671) and femur (p=0.126).Conclusion: As a result, 25(OH) D vitamin deficiency is quite common in transplant patientsand the loss of BMD is observed especially in the lumbar region in the first year aftertransplantation.
Açıklama
Anahtar Kelimeler
Kaynak
Düzce Tıp Fakültesi Dergisi
WoS Q Değeri
Scopus Q Değeri
Cilt
22
Sayı
1
