Serum uric acid levels in patients with type 2 diabetes Mellitus who have normal renal function

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dc.contributor.authorMemişoğulları, Ramazan
dc.contributor.authorYüksel, Hatice Kurt
dc.contributor.authorCoşkun, Abdurrahman
dc.contributor.authorŞahin, İbrahim Ethem
dc.contributor.authorYavuz, Özlem
dc.date.accessioned2020-04-30T23:31:54Z
dc.date.available2020-04-30T23:31:54Z
dc.date.issued2007
dc.departmentDÜ, Tıp Fakültesi, Temel Tıp Bilimleri Bölümüen_US
dc.descriptionCoskun, Abdurrahman/0000-0002-1273-0604en_US
dc.descriptionWOS: 000254852600005en_US
dc.description.abstractThe aim of this study was to investigate whether serum uric acid levels increase in Diabetes Mellitus and if serum uric acid levels were related to factors apart from hypertension and renal failure. Fifty-five newly diagnosed patients with type 2 Diabetes Mellitus and 41 healthy volunteers were included in the study. Serum creatinin level, total cholesterol level, low density lipoprotein-cholesterol level, body mass index, age, and arterial blood pressure was not different in diabetic group, when compared with the control group. However, serum uric acid level (4.6 +/- 1.5 mg/dL) was significantly lower than those of the control group (5.3 +/- 1.7 mg/dL) (p<0.05). In addition, uric acid in the diabetic group did not significantly correlate with the biochemical and clinical variables, whereas in the control group, serum uric acid level was significantly correlated with systolic blood pressure, diastolic blood pressure, fasting blood glucose level, hemoglobin A(1C) level and body mass index. We think that decreased serum uric acid level in diabetes is dependent on many factors. In addition, the decrease of serum uric acid level may be contributed to oxidative stress in diabetes.en_US
dc.identifier.endpage75en_US
dc.identifier.issn0250-4685
dc.identifier.issn1303-829X
dc.identifier.issue2en_US
dc.identifier.startpage72en_US
dc.identifier.urihttps://hdl.handle.net/20.500.12684/4523
dc.identifier.volume32en_US
dc.identifier.wosqualityN/Aen_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.language.isotren_US
dc.publisherWalter De Gruyter Gmbhen_US
dc.relation.ispartofTurkish Journal Of Biochemistry-Turk Biyokimya Dergisien_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectdiabetes mellitusen_US
dc.subjecturic aciden_US
dc.subjectfasting blood glucoseen_US
dc.titleSerum uric acid levels in patients with type 2 diabetes Mellitus who have normal renal functionen_US
dc.typeArticleen_US

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