Evaluation of toxoplasma, rubella, and cytomegalovirus seroprevalence and avidity testing in pregnant women

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dc.contributor.authorKeskin, Banu Humeyra
dc.contributor.authorOner, Betul Altintas
dc.date.accessioned2026-07-01T11:39:37Z
dc.date.available2026-07-01T11:39:37Z
dc.date.issued2025
dc.departmentDüzce Üniversitesi
dc.description.abstractObjectives: This study aimed to determine the seroprevalence of Toxoplasma, Rubella, and Cytomegalovirus (CMV) pathogens capable of transplacental transmission leading to significant perinatal morbidity and mortality in pregnant women, and to provide updated regional data for clinical guidance. Methodology: In this retrospectively study toxoplasma, rubella and CMV antibody results studied using electrochemiluminescence immunoassay in the sera of pregnant women who applied to Zonguldak Gynecology and Obstetrics Hospital between June 2022 and June 2024 were retrospectively analyzed. Results: Among 2816 pregnant women, IgG seropositivity was observed in 697 (24.8%) for Toxoplasma gondii, 2623 (93.6%) for Rubella, and 2755 (98.3%) for CMV. IgM seropositivity was found in 62 (2.2%), 18 (0.6%), and 21 (0.7%) patients, respectively. Toxoplasma IgG seropositivity was significantly higher in women aged >= 40 years, while Rubella IgG positivity peaked in the 25-29 age group (p<0.05). Conclusion: In conclusion, the rate of Toxoplasma seronegativity found in our study suggests that screening of women would be beneficial and that studies of these infections, in which regional differences in seroprevalence are observed, would contribute to the development of appropriate strategies for screening.
dc.identifier.doi10.12669/pjms.41.9.12453
dc.identifier.endpage2599
dc.identifier.issn1682-024X
dc.identifier.issn1681-715X
dc.identifier.issue9
dc.identifier.orcid0000-0002-2102-3952
dc.identifier.pmid41070306
dc.identifier.startpage2595
dc.identifier.urihttps://doi.org/10.12669/pjms.41.9.12453
dc.identifier.urihttps://hdl.handle.net/20.500.12684/23372
dc.identifier.volume41
dc.identifier.wosWOS:001588821000026
dc.identifier.wosqualityQ2
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakPubMed
dc.language.isoen
dc.publisherProfessional Medical Publications
dc.relation.ispartofPakistan Journal of Medical Sciences
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanı
dc.rightsinfo:eu-repo/semantics/openAccess
dc.snmzKA_WOS_20260623
dc.subjectCongenital Infection
dc.subjectCytomegalovirus
dc.subjectToxoplasma
dc.subjectPregnancy
dc.subjectRubella
dc.titleEvaluation of toxoplasma, rubella, and cytomegalovirus seroprevalence and avidity testing in pregnant women
dc.typeArticle

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