Clinical significance of mean platelet volume, platelet distribution width, and neutrophil-lymphocyte ratio in children with familial mediterranean fever
Küçük Resim Yok
Tarih
2024
Dergi Başlığı
Dergi ISSN
Cilt Başlığı
Yayıncı
Hatay Mustafa Kemal Üniversitesi
Erişim Hakkı
info:eu-repo/semantics/openAccess
Özet
Objective: Familial Mediterranean Fever (FMF) is an autosomal recessive disease characterized by recurrent fever and polyserositis. Studies conducted in recent years emphasize the importance of platelet parameters in chronic diseases. This study examined changes in attack and attack-free periods in children with FMF, focusing on Mean Platelet Volume (MPV), an indicator of disease severity. Method: 150 FMF patients (90 girls, 60 boys) and 50 healthy individuals (29 men, 21 women) were included in the study. Data were analyzed according to colchicine treatment, attack, and attack-free periods. The severity of the disease was classified as mild, moderate, and severe. Results: MPV levels of patients with FMF were higher than the healthy group. In particular, MPV levels decreased significantly during attacks, with a more pronounced decrease in severe cases. Conclusion: As a result, MPV measurement is a cost-effective and rapid method that can support the evaluation of disease severity and attack periods in FMF patients.
Açıklama
Anahtar Kelimeler
Familial Mediterranean Fever|MPV|Neutrophil/Lymphocyte Ratio|M694V|PDW
Kaynak
Interdisciplinary Medical Journal
WoS Q Değeri
Scopus Q Değeri
Cilt
15
Sayı
52
