Evaluation of mean platelet volume, neutrophil/ lymphocyte ratio and platelet/lymphocyte ratio in advanced stage endometriosis with endometrioma

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dc.contributor.authorYavuzcan, Ali
dc.contributor.authorÇağlar, Mete
dc.contributor.authorÜstün, Yusuf
dc.contributor.authorDilbaz, Serdar
dc.contributor.authorÖzdemir, İsmail
dc.contributor.authorYıldız, Elif
dc.contributor.authorKumru, Selahattin
dc.date.accessioned2020-04-30T13:32:27Z
dc.date.available2020-04-30T13:32:27Z
dc.date.issued2013
dc.departmentDÜ, Tıp Fakültesi, Cerrahi Tıp Bilimleri Bölümüen_US
dc.description.abstractObjective: We compared the preoperative values of mean platelet volume (MPV) and peripheral systemic inflammatory response (SIR) markers (neutrophil/lymphocyte ratio and platelet/lymphocyte ratio) between patients with advanced-stage (stage 3/4) endometriosis having endometrioma (OMA) and patients with a non-neoplastic adnexal mass other than endometrioma (non-OMA). Material and Methods: Patients who underwent operations with the pre-diagnosis of infertility or adnexal mass and who underwent laparoscopic tubal ligation were included. Results: Haemoglobin levels, leucocyte count, platelet count, neutrophil count and lymphocyte count were not significantly different between patients with advanced stage endometriosis having OMA, patients with non-OMA and patients in the control group (p=0.970, p=0.902, p=0.373, p=0.501 and p=0.463, respectively). Patients with stage 3/4 endometriosis having OMA, patients with non-OMA and control patients were also not significantly different in terms of MPV (p=0.836), neutrophil/lymphocyte ratio (NLR) (p=0.555) and platelet/ lymphocyte ratio (PLR) (p=0.358). Preoperative cancer antigen 125 (Ca-125) levels were significantly higher in patients with OMA (p=0.006). Mean size of the OMAs was significantly lower than non- OMAs (p=0.000). Conclusion: It is very important to determine advanced stage endometriosis and OMAs during preoperative evaluation in order to inform patients and plan an appropriate surgical approach. We demonstrate that MPV, NLR and PLR values are not useful for this purpose in patients with advanced stage endometriosis that are proven to develop severe inflammation at either the cellular or molecular level. © 2013 by the Turkish-German Gynecological Education and Research Foundation.en_US
dc.identifier.doi10.5152/jtgga.2013.55452en_US
dc.identifier.endpage215en_US
dc.identifier.issn1309-0399
dc.identifier.issue4en_US
dc.identifier.scopusqualityQ3en_US
dc.identifier.startpage210en_US
dc.identifier.urihttps://dx.doi.org/10.5152/jtgga.2013.55452
dc.identifier.urihttps://hdl.handle.net/20.500.12684/301
dc.identifier.volume14en_US
dc.indekslendigikaynakScopusen_US
dc.language.isoenen_US
dc.relation.ispartofJournal of the Turkish German Gynecology Associationen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.subjectEndometriosis; Mean platelet volume; Neutrophil/lymphocyte ratio; Platelet/lymphocyte ratioen_US
dc.titleEvaluation of mean platelet volume, neutrophil/ lymphocyte ratio and platelet/lymphocyte ratio in advanced stage endometriosis with endometriomaen_US
dc.title.alternativeEndometrioma bulunan ileri evre endometrioziste ortalama trombosit hacmi, nötrofil/lenfosit oranı ve trombosit/lenfosit oranının de?erlendirilmesien_US
dc.typeArticleen_US

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