Evaluation of false negativity of the Widal test among culture proven typhoid fever cases

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dc.contributor.authorHoşoğlu, Salih
dc.contributor.authorBoşnak, Vuslat
dc.contributor.authorAkalın, Şerife
dc.contributor.authorGeyik, Mehmet Faruk
dc.contributor.authorAyaz, Celal
dc.date.accessioned2020-05-01T12:16:41Z
dc.date.available2020-05-01T12:16:41Z
dc.date.issued2008
dc.departmentDÜ, Tıp Fakültesi, Dahili Tıp Bilimleri Bölümüen_US
dc.descriptionGeyik, Mehmet Faruk/0000-0002-0906-0902en_US
dc.descriptionWOS: 000208250300013en_US
dc.descriptionPubMed: 19745527en_US
dc.description.abstractBackground: The Widal test is the most common, specific and quick diagnostic method available in the world for diagnosis of typhoid fever; however, false negativity is one of the obstructive features of the test. The aim of this study was to evaluate the associated factors with Widal test negativity in an endemic area. Methods: Widal test negativity was retrospectively analyzed among culture-proven typhoid fever cases. The potential features including age, gender, previous antibiotic usage, duration of symptoms, leucopoenia, hematocrit value, and erythrocyte sedimentation rate (ESR) were evaluated for association with Widal test negativity. Results: A total of 166 culture-proven typhoid fever cases (93 or 56.0% males) were included in the study. The mean age +/- SD was 23.3 +/- 10.6 years. Mean time of interval between first symptom and test performance time was 10.6 +/- 7.8 days. The Widal test (STO and/or STH) was found positive in 75 cases (45.2%). The statistical analyses revealed that none of these variables were significant for false negativity of the Widal test. Age was found to be a possible factor for a false negative Widal test (p=0.06). Conclusion: Of existing compatible clinical findings, age should be considered in cases of Widal test negativity.en_US
dc.identifier.endpage478en_US
dc.identifier.issn1972-2680
dc.identifier.issue6en_US
dc.identifier.startpage475en_US
dc.identifier.urihttps://hdl.handle.net/20.500.12684/6410
dc.identifier.volume2en_US
dc.identifier.wosqualityN/Aen_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoenen_US
dc.publisherJ Infection Developing Countriesen_US
dc.relation.ispartofJournal Of Infection In Developing Countriesen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.subjecttyphoid feveren_US
dc.subjectWidal testen_US
dc.subjectdiagnosisen_US
dc.titleEvaluation of false negativity of the Widal test among culture proven typhoid fever casesen_US
dc.typeArticleen_US

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