Which Humulus lupulus drug samples meet the European Pharmacopoeia criteria: Cultivated, obtained from the herbalists or online shopping sites in Turkey

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dc.contributor.authorBektur, Zehra
dc.contributor.authorKarakuş, Methiye Mancak
dc.contributor.authorÇalışkan, Ufuk Koca
dc.date.accessioned2023-07-26T11:55:12Z
dc.date.available2023-07-26T11:55:12Z
dc.date.issued2022
dc.departmentDÜ, Eczacılık Fakültesi, Temel Eczacılık Bilimleri Bölümüen_US
dc.description.abstractHumulus lupulus L. (Hops), which belongs to the Cannabaceae family, originates from Asia and grows naturally in geographies with temperate climates such as Europe and North America. H. lupulus might have been brought to Turkey from Germany to be used mostly in beer production. The plant is also used for medicinal purposes due to its sedative and phytoestrogenic effects all over the world. Pharmacopoeia analyzes are important to confirm whether the subject drog has the properties specified in the pharmacopoeia in order to check its suitability before it is used for health purposes. For this reason, we aimed to evaluate features of the variety of hops plants: 1-cultivated in Bilecik/Turkey; 2-sold by herbalists and sold on online shopping sites. Obtained samples of hops were analyzed according to the 'Lupuli flos' monograph provided within the European Pharmacopoeia 8.0 (EP 8.0). Macroscopic, microscopic, thin-layer chromatography, matter extractable by ethanol, loss on drying analyzes and determination of total ash amount of the samples were conducted according to the EP 8.0. As a result, the hop samples, except those cultured in Turkey, were not suitable for the EP 8.0. Legal controls should be provided by the authorities on herbals sold by herbalists and on the internet. Samples of hops cultured for use in beer production in Turkey were suitable for pharmacopoeia. These samples should meet the public at secure sales points or in food supplements in Turkey.en_US
dc.identifier.doi10.29228/jrp.222
dc.identifier.endpage1316en_US
dc.identifier.issn2630-6344
dc.identifier.issue5en_US
dc.identifier.scopus2-s2.0-85137869434en_US
dc.identifier.scopusqualityQ3en_US
dc.identifier.startpage1304en_US
dc.identifier.urihttps://doi.org/10.29228/jrp.222
dc.identifier.urihttps://hdl.handle.net/20.500.12684/13021
dc.identifier.volume26en_US
dc.identifier.wosWOS:000929825400020en_US
dc.identifier.wosqualityN/Aen_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.institutionauthorÇalışkan, Ufuk Koca
dc.language.isoenen_US
dc.publisherMarmara Univen_US
dc.relation.ispartofJournal of Research In Pharmacyen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.snmz$2023V1Guncelleme$en_US
dc.subjectHumulus Lupulus; Hops; European Pharmacopoeia; Cannabaceae; Herbalist.en_US
dc.subjectHop Extracts; 8-Prenylnaringenin; Xanthohumolen_US
dc.titleWhich Humulus lupulus drug samples meet the European Pharmacopoeia criteria: Cultivated, obtained from the herbalists or online shopping sites in Turkeyen_US
dc.typeArticleen_US

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