Aquasomes: a novel platform for drug delivery

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dc.authorscopusid57203248807
dc.authorscopusid57192876108
dc.authorscopusid55188530700
dc.authorscopusid35774636300
dc.authorscopusid57984416700
dc.contributor.authorİlhan, Miray
dc.contributor.authorGültekin, Hazal Ezgi
dc.contributor.authorRençber, S.
dc.contributor.authorŞenyiğit, Zeynep
dc.contributor.authorAydın, H.H.
dc.date.accessioned2023-07-26T11:53:47Z
dc.date.available2023-07-26T11:53:47Z
dc.date.issued2022
dc.departmentDÜ, Eczacılık Fakültesi, Eczacılık Teknolojisi Bölümüen_US
dc.description.abstractIn recent years, drug research has focused on nanocarrier systems. Self-assembled nanodrug delivery systems such as liposome, niosome, polymersome, and transfersome maintain their popularity as drug research subjects. Aquasomes are also in the class of self-assembled drug delivery systems, but they are not vesicular systems. Aquasomes are formed by the coating of polyhydroxyl oligomers on a solid crystal core. The drug is adsorbed on this oligomer layer, and a three-layer structure is obtained. Aquasomes have two important advantages over other nanoparticular systems. First, the crystal core increases the stability of the particle, and second, the carbohydrate layer provides the appropriate layer for the active substance to be adsorbed. In addition, although it is stated in the literature that it is generally suitable for the delivery of biological molecules such as proteins, antigens, and nucleic acids, since it is a system that can protect the active pharmaceutical ingredient against dehydration, there are also studies for some small molecule drugs. © 2022 Elsevier Inc. All rights reserved.en_US
dc.identifier.doi10.1016/B978-0-323-91864-0.00020-6
dc.identifier.endpage206en_US
dc.identifier.isbn9780323918640
dc.identifier.isbn9780323914222
dc.identifier.scopus2-s2.0-85142786328en_US
dc.identifier.startpage191en_US
dc.identifier.urihttps://doi.org/10.1016/B978-0-323-91864-0.00020-6
dc.identifier.urihttps://hdl.handle.net/20.500.12684/12601
dc.indekslendigikaynakScopusen_US
dc.institutionauthorİlhan, Miray
dc.language.isoenen_US
dc.publisherElsevieren_US
dc.relation.ispartofSystems of Nanovesicular Drug Deliveryen_US
dc.relation.publicationcategoryKitap Bölümü - Uluslararasıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.snmz$2023V1Guncelleme$en_US
dc.subjectAquasomesen_US
dc.subjectbodies of wateren_US
dc.subjectbrushiteen_US
dc.subjectcalcium phosphateen_US
dc.subjectceramic coreen_US
dc.subjectceramic nanoparticlesen_US
dc.subjectnanocarriersen_US
dc.subjectoligomersen_US
dc.subjectself-assembling nanocarrieren_US
dc.subjecttargeted drug deliveryen_US
dc.titleAquasomes: a novel platform for drug deliveryen_US
dc.typeBook Chapteren_US

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