The Clinical Correlations of Fatigue in Patients with Sarcoidosis

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dc.contributor.authorGülhan, Pınar Yıldız
dc.contributor.authorBalbay, Ege Güleç
dc.contributor.authorKumbasar, Özlem Özdemir
dc.contributor.authorErçelik, Merve
dc.contributor.authorAnnakkaya, Ali Nihat
dc.contributor.authorArbak, Peri Meram
dc.date.accessioned2023-07-26T11:51:09Z
dc.date.available2023-07-26T11:51:09Z
dc.date.issued2022
dc.departmentDÜ, Tıp Fakültesi, Dahili Tıp Bilimleri Bölümü, Göğüs Hastalıkları Ana Bilim Dalıen_US
dc.description.abstractObjective: Fatigue is considered a frequent and characteristic feature of sarcoidosis. This study was designed to determine the prevalence of fatigue in patients with sarcoidosis and to determine its potential clinical correlations in relation to symptom severity. Methods: A total of 56 sarcoidosis patients were included. Data on patient demographics, anthropometrics, disease characteristics, pulmonary function tests, 6-min walking distance (6MWD), blood biochemistry and hemogram findings were retrieved from hospital records. Psychometric instruments involved fatigue assessment scale (FAS), Beck Depression Inventory (BDI) and Short Form-36 (SF-36) for health-related QOL (HRQOL). Results: Mean±SD patient age was 50.9±11.9 years. Of 56 patients, 44 were females and 12 were males. When compared to FAS score <22 and FAS score ?22-34 subgroups, FAS score ?35 (severe fatigue) subgroup was associated with significantly higher patient age and significantly lower SF-36 physical health scores. Total FAS scores were correlated positively with age (r=0.349, p=0.008) and BDI scores (r=0.515, p<0.001), while negatively with MIP (r=-0.321, p=0.019) and SF-36 physical health (r=-0.402, p=0.003) and mental health (r=-0.351, p=0.009) scores. BDI score (OR 1.146, 95% CI: 1.020 to 1.288, p=0.021) was determined to be the single independent predictor of increased likelihood of a patient with sarcoidosis to have FAS score ?22. Conclusions: Our findings emphasize that deterioration in respiratory functions may contribute to development of fatigue among sarcoidosis patients, and besides the fatigue, depressive symptoms and anxiety should also be an integral part of the multidisciplinary management of sarcoidosis patients.en_US
dc.identifier.endpage502en_US
dc.identifier.issn1309-3878
dc.identifier.issue3en_US
dc.identifier.startpage497en_US
dc.identifier.trdizinid1138398en_US
dc.identifier.urihttps://search.trdizin.gov.tr/yayin/detay/1138398
dc.identifier.urihttps://hdl.handle.net/20.500.12684/12505
dc.identifier.volume14en_US
dc.indekslendigikaynakTR-Dizinen_US
dc.institutionauthorArbak, Peri Meram
dc.language.isoenen_US
dc.relation.ispartofKONURALP TIP DERGİSİen_US
dc.relation.publicationcategoryMakale - Ulusal Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.snmz$2023V1Guncelleme$en_US
dc.titleThe Clinical Correlations of Fatigue in Patients with Sarcoidosisen_US
dc.typeArticleen_US

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