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Öğe Akut Pankreatit Şiddeti ile Trombosit Lenfosit Oranı, Nötrofil Lenfosit Oranı, Eritrosit Dağılım Genişliği ve Ortalama Platelet Volümü Arasındaki İlişki(2019) Önmez, Atilla; Bilir, Ece; Torun, SerkanAmaç: Bu çalışmada sistemik inflamasyon ile ilişkili bir marker olduğu gösterilen; Nötrofillenfosit oranı (NLR), platelet-lenfosit oranı (PLR), ortalama trombosit hacmi (MPV) veEritrosit dağılım hacmi (RDW) ile akut pankreatitin (AP) başvuru anındaki ciddiyetinigösteren Ranson kriteri ile aralarındaki ilişkinin gösterilmesi amaçlanmıştır.Gereç ve Yöntem: Ocak 2017 ile Kasım 2018 tarihleri arasında AP tanısı ile takip edenhastaların verilerine retrospektif olarak ulaşıldı. 82 biliyer ve 15 nonbiliyer olmak üzeretoplam 139 hasta çalışmaya alındı. Hastaların ilk başvuru anında bakılan hemogram vebiyokimyasal parametreleri, yaşları, cinsiyetleri, ko-morbiditeleri ve yatış süreleri kaydedildi.İlk başvuru anında bakılan Ranson Kriterlerine göre skoru < 3 ve skoru ? 3 pozitif olanlarolmak üzere 2 gruba ayrıldı ve bu gruplar karşılaştırıldı.Bulgular: AP tanısı ile takip edilen 139 hastanın 75 (%54)’i erkek, 64 (%46)’ü kadındı.Hastaların 113’ü Ranson kriterlerine göre 3’ün altında 26’sı ise 3 ve üzerindeydi. Ortalamayaş hafif AP grubunda 61±20 yıl, şiddetli AP grubunda ise 70±13 yıldı. MPV (P< 0.001) veNLR (P< 0.001) değerleri gruplar arasında anlamlı olarak farklı saptandı. Korelasyonanalizinde; NLR ile ranson skoru arasında pozitif korelasyon saptandı (r= 0,253 p<0,01).Yapılan Lineer Regresyon analizi sonucunda, NLR ve PLR’nin AP şiddetini göstermedebağımsız prediktör oldukları bulundu.Sonuç: Sistemik inflamasyonu gösteren çalıştığımız parametrelerden NLR, AP’nin şiddetinibelirlemede basit ve güvenilir bir gösterge olarak kullanılabilir.Öğe Benign karaciğer hastalıklarında endoskopik ultrason eşliğinde ince iğne aspirasyonu: Tek merkez deneyimi(2023) Tokmak, Salih; Kantarcıoğlu Coşkun, Sinem; Torun, SerkanGiriş ve Amaç: Endoskopik ultrason kılavuzluğunda karaciğer biyopsisi (EUS-LB) ile ilgili ilk deneyimimizin etkinlik ve güvenlik sonuçlarını bildirmek. Gereç ve Yöntem: Üçüncü basamak merkezimizde, ileriye dönük olarak tutulan bir veri tabanının geriye dönük analizi yapıldı. Haziran 2022 ile Aralık 2022 tarihleri arasında, benign parankimal hastalıklar nedeniyle, tek geçişli, üç hamleli ve ıslak aspirasyon tekniği ve 19 gauge ince iğne kullanılarak EUS-LB uygulanan ardışık hastalar çalışmaya dahil edildi. Hastaların demografik bilgileri, işlem ile ilgili parametreler ve örneklerin kalitesi değerlendirildi. Sonuçlar: Teknik başarı %100 idi. Toplam 16 hastadan dördüne yetersiz örnekleme nedeniyle ikinci kez işlem uygulandı. Medyan toplam numune uzunluğu, medyan parça sayısı ve parçalanmış numunelerdeki en uzun parçanın medyan uzunluğu ve tam portal yolların medyan sayısı sırayla 11 mm (aralık, 0,2-2,5), 9,6 (aralık, 0-20), 0,2mm (aralık 0,2-1,5) ve 3,5 (aralık 0-19) olarak bulundu. İşlem sonrası hiçbir hastada yan etki görülmedi. Sonuç: EUS-LB, diğer karaciğer biyopsi prosedürlerine bir alternatif olabilir, ancak ideal iğne tipini ve tekniğini belirlemek için daha fazla çalışmaya ihtiyaç vardır.Öğe Choledocholithiasis without Cholecystolithiasis, After Endoscopic Retrograde Cholangiopancreatography Follow-Up without Cholecystectomy(2021) Muhammedoğlu, Bahtiyar; Pircanoğlu, Eyüp Mehmet; Torun, SerkanObjective: The widespread use of imaging methods increases the diagnosis and incidence of cholelithiasis. In recent years, management of patients with cholelithiasishas improved significantly owing to significant advances in surgical and endoscopic intervention.Methods: Between February 2015 and January 2018, the data of patients who underwent ERCP at our institution were collected prospectively and analyzed retrospectively. Forty-four patients included in the study were patients with choledocholithiasis without stones in the GB.Results: The mean age of 52 subjects (group A) included in the study was 64.83 ± 17.06, of which 23 (44.2%) were <65 years old and 29 (55.8%) were ?65 years old. Twenty-four (46.2%) women and twenty-eight (53.8%) men were included in the study. Malignancy was suspected in 6 (11.5%) patients and no suspicion of malignancy was confirmed after Endoscopic Retrograde Cholangio-Pancreatography (ERCP) procedure. In group A, 14 patients (26.9%) required a second ERCP, while in group B, the number of patients requiring a second ERCP was 163 (21.3%). The mean length of hospital stay in group A and group B patients was 5.29 ± 3.38 and 6.29 ± 5.39, respectively, and the average cost was 474 $ ± 286 $ and 564 $ ± 664 $, respectively, with no statistical difference between the groups.Conclusions: In conclusion, we think that in patients with secondary or primary choledochal stones without gallstones and with functional GB might be following up without cholecystectomy after the stone is removed from the bile duct by ERCP.Öğe A Critically Ill Patient with Aspergillus Fumigatus Sepsis-Related Ischemic Colitis(Erciyes Univ Sch Medicine, 2022) Akbaş, Türkay; Coşkun, Gökhan; Torun, Serkan; Akın, Gül; Önbaş, ÖmerBackground: Invasive aspergillosis (IA) is an opportunistic infection generally encountered in patients with hematological malignancies. However, IA is increasingly recognized in non-neutropenic and critically ill patients in the absence of classic risk factors.Case Report: An 81-year-old man with diabetes mellitus (DM), chronic renal failure (CRF), and heart failure, who had had 1-week complaints of diarrhea, nausea, and vomiting, was admitted to the intensive care unit with septic shock, acute respi-ratory failure, and acute kidney injury. Chest computed tomography showed cavitary lung lesions and colonoscopy revealed ischemic ulcers in the descending colon. Other causes of cavitary lung lesions were excluded and all cultures were negative, except for bronchoalveolar lavage yielding Aspergillus fumigatus. Thus, Aspergillus fumigatus sepsis with multiorgan failures was diagnosed.Conclusion: Inhaled Aspergillus conidia are kept under control by alveolar macrophage. DM, CRF, and aging are the con-ditions that disrupt phagocytic activity of macrophages and predispose to IA.Öğe A Critically Ill Patient with Aspergillus Fumigatus Sepsis-Related Ischemic Colitis(2022) Coşkun, Gökhan; Torun, Serkan; Akbaş, Türkay; Akin, Gul; Önbaş, ÖmerBackground: Invasive aspergillosis (IA) is an opportunistic infection generally encountered in patients with hematological malignancies. However, IA is increasingly recognized in non-neutropenic and critically ill patients in the absence of classic risk factors. Case Report: An 81-year-old man with diabetes mellitus (DM), chronic renal failure (CRF), and heart failure, who had had 1-week complaints of diarrhea, nausea, and vomiting, was admitted to the intensive care unit with septic shock, acute respi- ratory failure, and acute kidney injury. Chest computed tomography showed cavitary lung lesions and colonoscopy revealed ischemic ulcers in the descending colon. Other causes of cavitary lung lesions were excluded and all cultures were negative, except for bronchoalveolar lavage yielding Aspergillus fumigatus. Thus, Aspergillus fumigatus sepsis with multiorgan failures was diagnosed. Conclusion: Inhaled Aspergillus conidia are kept under control by alveolar macrophage. DM, CRF, and aging are the con- ditions that disrupt phagocytic activity of macrophages and predispose to IA.Öğe The effect of COVID-19 lockdown on glycemic control in patients with type 2 diabetes mellitus in Turkey(Elsevier Sci Ltd, 2020) Onmez, Attila; Gamsizkan, Zerrin; Ozdemir, Seyma; Kesikbas, Enis; Gokosmanoglu, Feyzi; Torun, Serkan; Cinemre, HakanBackground and aims: A national lockdown to prevent the spread of coronavirus disease (COVID-19) in Turkey was introduced in March 2020. We think that lockdowns may lead to weight gain and worsening of glycemic parameters in patients with type 2 diabetes mellitus (DM). The purpose of this study was to investigate how type 2 DM patients were affected by the lockdown. Method: Type 2 DM patients unable to attend regular follow-ups due to lockdown over a 75-day period between March and June 2020 and who again attended polyclinic follow-up when the lockdown was lifted were included in the study. These patients' glycemic control and weight status were compared with the pre-lockdown period. In addition, patients' general habits, and adherence to diet and exercise were evaluated, while their general health was assessed using the Short-Form 36-item survey. Result: The research involved 101 type 2 DM patients, 57 men (56.5%) and 44 women (44.5%), with a mean age of 55 +/- 13. Patients' mean pre-lockdown weight was 84.7 +/- 16.4 kg, rising to 85.5 +/- 16.8 kg post-lockdown, although the increase was not statistically significant (p = 0.781). In terms of glycemic parameters, Hba1c rose from 7.67 +/- 1.76 to 8.11 +/- 2.48, and fasting glucose from 157.9 (83-645) mg/dl to 163.2 (84-550) mg/dl, none of which were statistically significant (p = 0.253, p = 0.079, respectively). Conclusion: In addition to weight gain among type 2 DM patients during the Covid 19 lockdown, statistically insignificant increases were also observed in such glycemic parameters. This was a small sample and further studies with larger sample are needed. (C) 2020 Diabetes India. Published by Elsevier Ltd. All rights reserved.Öğe Efficacy and safety of endoscopic retrograde cholangiopancreatography in the very elderly by using a combination of intravenous midazolam, ketamine and pethidine(Wiley, 2021) Tokmak, Salih; Cetin, Mehmet F.; Torun, SerkanAim The number of therapeutic endoscopic procedures in elderly individuals keeps increasing and this population has a high risk of adverse events related to sedation and general anesthesia. However, there is a paucity on data about the efficacy and safety of endoscopic retrograde cholangiopancreatography (ERCP) in this population. Methods In total, 417 consecutive ERCP procedures were performed in 362 patients between September 2018 and January 2020. Of these, 59 patients (74 sessions) were aged >= 80 years (Group A) and 173 patients (193 procedures) were aged <= 65 years (Group B). We analyzed the prospectively collected data of patient- and procedure-related variables. Results The procedure time was significantly longer in Group A (P < 0.05). The prevalence of comorbidities, use of anticoagulants and American Society of Anesthesiologists (ASA) physical status classification levels were significantly higher in Group A (P < 0.05). The incidence of periampullary diverticula, malignancy, rate of difficult cannulation, mean number of stones, use of biliary stents and stent dysfunction was also significantly higher in Group A (P < 0.05). The medication doses used were significantly higher and emergence symptoms were significantly more frequent in Group B (P < 0.05). The rates of bleeding, pancreatitis, perforation, cholangitis, hypoxia, hypotension and the length of hospital stay did not significantly differ between the two groups. The overall success rate of the procedure was comparable in the two groups (P = 0.874). Conclusions ERCP can be safely performed in elderly patients using a combination of midazolam and ketamine without propofol. The incidence of complications is comparable with that observed in younger patients. Geriatr Gerontol Int center dot center dot; center dot center dot: center dot center dot-center dot center dot Geriatr Gerontol Int 2021; center dot center dot: center dot center dot-center dot center dot.Öğe Efficacy of Epinephrine Injection in Preventing Post-ERCP Pancreatitis(Lippincott Williams & Wilkins, 2021) Torun, Serkan; Odemis, Bulent; Cetin, Mehmet F.; Onmez, Attila; Coskun, OrhanBackground: Rectal indomethacin or a topical spray of epinephrine to the papilla of Vater has each shown efficacy alone in the prevention of post-endoscopic retrograde cholangiopancreatography pancreatitis (PEP). We supposed that a submucosal epinephrine injection would be more effective and longer acting than a topical epinephrine spray and therefore would further reduce the incidence of PEP. Patients and Methods: A retrospective analysis was conducted of 412 patients who underwent endoscopic retrograde cholangiopancreatography (ERCP) between January 2017 and December 2019. These patients were divided into 2 groups: the indomethacin group and the indomethacin plus the submucosal epinephrine injection group. The incidence rates and severity of PEP, post-ERCP hyperamylasemia, other outcomes, and any other adverse events were compared between the groups. Results: Baseline demographic and clinical characteristics and procedure-related parameters were similar between the 2 groups. The incidence of PEP was 0.4% in the epinephrine group compared with 5.1% in the indomethacin group (P <0.001). Post-ERCP hyperamylasemia occurred in 24.6% of patients in the indomethacin group, whereas 7.6% of patients in the epinephrine group developed this condition; the difference was significant (P <0.001). Postsphincterotomy bleeding occurred in 5 patients, all of whom were in the indomethacin group (P < 0.001). Other adverse events, including arrhythmias, acute coronary events, stroke, or hypertension were not significantly different between the 2 groups. Conclusion: Addition of a submucosal epinephrine injection in conjunction with rectal indomethacin significantly reduced the incidence of PEP, post-ERCP hyperamylasemia, and post-sphincterotomy bleeding.Öğe Öğe Feasibility and safety of partial ampullary endoscopic mucosal resection: a novel technique for difficult biliary cannulation (with video)(Springer, 2022) Tokmak, Salih; Çetin, Mehmet Fuat; Torun, SerkanBackground Biliary cannulation can be challenging even for expert endoscopists, and rescue techniques are limited. Our objective was to determine the feasibility and safety of partial ampullary endoscopic mucosal resection (PA-EMR), a novel technique for biliary cannulation. Methods Monocentric, retrospective analysis of a prospectively maintained database in a tertiary referral university hospital. Fourteen patients who required endoscopic retrograde cholangiopancreatography (ERCP) and underwent PA-EMR between January 1, 2020 and January 31, 2021 were included. For biliary cannulation of prominent papillae, PA-EMR was performed using a standard polypectomy snare, alone or in combination with needle-knife sphincterotomy. In patients with non-prominent papilla, the papillary mucosa was elevated with the aid of methylene blue injection before resection and combined with needle-knife fistulotomy when needed. The rate of technical success and adverse events was assessed. Results The bile duct cannulation success was 99% in the first attempt and 100% overall with the PA-EMR technique. Only one patient experienced mild bleeding, which spontaneously stopped. Conclusion PA-EMR is an effective technique that may be considered as a rescue technique for difficult biliary cannulation in expert hands. Future studies including larger cohorts and comparisons with other techniques are warranted to further confirm the feasibility and safety of this novel technique.Öğe Gastric squamous cell carcinoma: A case report [Gastrik skuamöz hücreli karsinom: Olgu sunumu](Duzce University Medical School, 2019) Gamsızkan, Mehmet; Torun, Serkan; Doğan, SamiGastric squamous cell carcinoma is rarely seen and affects mostly elder patients. A 78-year-old woman presented with nausea, vomiting, weight loss, and epigastric pain. There was an ulcero-vegetative mass in the posterior area from the large curvature to the antrum in the endoscopic examination. The gastroesophageal junction and cardia were also normal. We performed a diagnostic endoscopic biopsy. Histopathologically, it was composed of atypical squamous cells displaying infiltrating solid nests in a desmoplastic stroma. Immunohistochemically, the neoplastic cells also showed positivity for p40 and p63 and negativity for CEA. Besides, there was no radiological evidence of metastasis from other organs. We herein presented a case of gastric squamous cell carcinoma and discussed its clinical and morphological features with the literature. © 2019, Duzce University Medical School. All rights reserved.Öğe Lumen reconstruction with magnetic compression anastomosis technique in a patient with complete esophageal stricture(Univ Catholique Louvain-Ucl, 2022) Ödemiş, Bülent; Başpınar, Batuhan; Durak, M. B.; Coşkun, O.; Torun, SerkanBackground: Complete esophageal obstruction (CEO) is a rare condition of which treatment options are challenging. Surgery is the main treatment with high morbidity and mortality rates. Magnetic compression anastomosis (MCA) is a novel technique developed to restore lumen patency in gastrointestinal and biliary tracts. However, MCA experience is limited in respect of esophageal strictures. Case Report: We present a 26-year-old patient having CEO. Magnets are inserted endoscopically to both sides of the obstructed area via oral and retrograde (through the gastrostomy tract) route. On day 8, magnets stuck together and were removed endoscopically through the oral route. Subsequently, sessions of balloon dilatations and triamcinolone injection were performed. The patient's complaint of aphagia resolved after the treatment process. Conclusion: In conclusion, MCA is an alternative technique that can be used to restore lumen patency in esophageal strictures and also avoids complications of surgical interventions. (Acta gastroenterol. belg., 2022, 85, 393-395).Öğe Magnet-assisted endoscopic choledochoduodenostomy in anomalous opening of the common bile duct into the duodenal bulb(Georg Thieme Verlag Kg, 2020) Odemis, Bulent; Baspinar, Batuhan; Torun, Serkan; Coskun, Orhan[Abstract Not Available]Öğe Magnetic Compression Anastomosis Is a Good Treatment Option for Patients with Completely Obstructed Benign Biliary Strictures: A Case Series Study(Springer, 2022) Ödemiş, Bülent; Başpınar, Batuhan; Tola, Muharrem; Torun, SerkanBackground Completely obstructed benign biliary strictures (BBS) is a difficult-to-treat condition. Surgery is the main treatment modality with high morbidity and mortality. Recently, the magnetic compression anastomosis (MCA) technique was employed in such cases with low complication rates. Aims To evaluate the effectiveness of the MCA in completely obstructed BBS. Methods 21 MCA procedures were performed in 19 patients with completely obstructed BBS. All patients had percutaneous biliary access. Magnets were located to the proximal side of the obstruction via percutaneous biliary sheath and the distal side endoscopically. The procedure was terminated as the magnets attracted. Either self-expandable fully covered metallic stent and/or a growing number of plastic stents were introduced after recanalization was achieved. Result A total number of 19 patients with completely obstructed BBS resulting from cholecystectomy or liver transplant underwent 21 MCA procedures. Among those, 19 (90.5%) interventions were successful. The median stricture length that had been measured after magnet attraction was 4 mm (range 1-10 mm). The median magnet coupling time in successful cases was 9 days (range 4-27 days). No correlation was found between magnet coupling time and stricture length (p = 0.27). Complications were observed in 6 (cholangitis:1, magnet migration:2, magnet entrapment:3) of 19 successful MCA procedures. Fifteen of the 19 successful procedures had at least a period of stent-free follow-up. Recurrence of stenosis occurred in 7 procedures, of which 4 remained stent-free with retreatment. Eventually, 12 procedures had stent-free last status. Conclusions MCA is an effective and safe treatment option in completely obstructed BBS. Further studies are required for procedural standardization.Öğe Metastatic Melanoma of the Common Bile Duct Presented with Dyspepsia(Korean Soc Gastroenterology, 2024) Cetiner, Omer Faruk; Dundar, Huseyin Emre; Kantarcioglu-Coskun, Sinem; Torun, Serkan; Tokmak, SalihMalignant melanoma (MM) is an aggressive tumor that can metastasize to any organ, but biliary tract metastasis is scarce. We describe a very rare case of MM metastasis to the common bile duct (CBD), presented with only dyspeptic symptoms. The patient had mildly elevated alkaline phosphatase and gamma-glutamyl transferase levels. Magnetic resonance cholangiopancreatography demonstrated a dilated common bile duct with a distal stricture. The MM diagnosis was established with the ampulla of Vater biopsy specimens obtained by endoscopic retrograde cholangiopancreatography (ERCP), and the patient's symptoms were resolved after biliary stenting. Both primary CBD cancer and other cancer types like MM that metastasize to CBD can cause obstruction and can be manifested only by dyspeptic symptoms. MM metastasis to CBD can cause obstruction manifested only by dyspeptic symptoms without obstructive jaundice. ERCP can be employed as a promising option for treatment and diagnosis. New-onset dyspeptic symptoms in patients with a history of MM should be investigated thoroughly, especially in the context of biliary metastasis.Öğe Pankreatik Nöroendokrin Karsinomda Paraneoplastik Ciddi Sensorimotor Aksonal Polinöropati: Vaka Sunumu ve Literatür Taraması(2022) Akbaş, Türkay; Kantarcıoğlu Coşkun, Sinem; Torun, Serkan; Öztürk, Ayhan; Eşbah, Onur; Onbas, OmerAmaç: Paraneoplastik nörolojik sendromlar (PNSs), kanser öncesi veya kanser sırasında gelişen, sinir sisteminin herhangi bir kısmını etkileyen çeşitli nörolojik hastalıkları içermektedir. Vaka: Yetmiş sekiz yaşında erkek hastanın üç yıl önce üst ekstremitelerde ağrı ve yanma hissi şikayetleri başlamış ve kısa süre sonra kas güçsüzlüğü eklenmiş. Bir yıl önce de alt ekstremitelerde benzer şikayetler ortaya çıkmış. Yoğun bakım ünitesine pnömoni tansıyla yatırılan hastanın yatış esnasında bilinci açık, fakat kuadriplejik ve modifiye Rankin skoru 5 idi. Abdomen bilgisayarlı tomografi karaciğer ve pankreasta kitle lezyonlarının olduğunu gösterdi. Lezyonyonlardan alınan biyopsiler pankreas orjinli küçük hücreli nöroendokrin karsinom olarak raporlandı. Elektrofizyolojik testler ciddi sensorimotor aksonal polinöropati ile uyumluluk gösteriyordu Diğer polinöropati nedenleri dışlandıktan sonra, hastaya paraneoplastik sensorimotor aksonal polinöropati tanısı konuldu. Hastanın fonksiyonel kapasitesi düşük olduğundan palyatif tedavi planlandı. Sonuç: PNS’li hastalarda uygun tedavinin başlanması için erken kanser tanısının konulması önem arz etmektedir.Öğe Paraneoplastic Severe Sensorimotor Axonal Polyneuropathy in Pancreatic Neuroendocrine Carcinoma: A Case Report and Review of the Literature(Duzce Univ, Fac Medicine, 2022) Akbaş, Türkay; Coşkun, Sinem Kantarcıoğlu; Torun, Serkan; Öztürk, Ayhan; Esbah, Onur; Önbaş, ÖmerObjective: Paraneoplastic neurological syndromes (PNSs) are a diverse group of neurological disorders affecting any part of the nervous system before or during cancer. Case: A 78-year-old man first experienced pain and burning in the upper extremity three years previously, to which muscle weakness was added a short time later. The same symptoms developed in the lower extremities one year previously. He was admitted to the intensive care unit due to pneumonia and was conscious but quadriplegic with a modified Rankin score of 5. Abdominal computed tomography showed mass lesions in the liver and pancreas. Biopsies revealed pancreatic small cell neuroendocrine carcinoma. Electrophysiological studies revealed severe sensorimotor axonal polyneuropathy. Paraneoplastic sensorimotor axonal polyneuropathy was diagnosed since other causes of polyneuropathy had been excluded. Palliative care was considered due to the patient's poor functional state. Conclusions: Early diagnosis of cancer is of paramount importance in patients with PNSs if appropriate treatment is to be provided.Öğe A rare case of a windsock-shaped intraluminal duodenal diverticulum treated successfully with endoscopic diverticulectomy(Georg Thieme Verlag Kg, 2022) Ödemiş, Bülent; Başpınar, Batuhan; Erdoğan, Çağdaş; Koç, Deniz Öğütmen; Coşkun, Banu Demet Özel; Torun, Serkan[Bastract Not Available]Öğe Reply to Letter to the Editor-Treatment of Hepatic Hydatid Disease-Role of Surgery, ERCP, and Percutaneous Drainage: A Retrospective Study(Lippincott Williams & Wilkins, 2021) Muhammedoglu, Bahtiyar; Pircanoglu, Eyup M.; Piskin, Erol; Torun, Serkan; Karadag, Mehmet; Topuz, Sezgin; Koktas, Suleyman[Abstract Not Available]Öğe Response to the letter to the editor sedation strategy for retrograde cholangiopancreatography in older patients by He et al.(Wiley, 2022) Tokmak, Salih; Çetin, Mehmet Fuat; Torun, Serkan[Bastract Not Available]