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Öğe Alterations in thyroid hormones in brain-dead patients are related to non-thyroidal illness syndrome(Via Medica, 2018) Akbaş, Türkay; Şahin, İbrahim Ethem; Öztürk, AyhanIntroduction: Alterations in thyroid hormone levels occur in patients with acute neurological disease states. The aim of this study is to study changes in thyroid hormones in patients with brain death (BD). Material and methods: Eleven brain-dead patients were studied prospectively. Thyroid hormones were measured on admission to the intensive care unit, the day before BD diagnosis (BD before), and the day after BD diagnosis (BD day). Results: Thyroid stimulating hormone (TSH) and free triiodothyronine (fT3) concentrations were found to be significantly low on admission, BD before, and BD day compared to age-matched healthy controls. TSH levels were shown to be increasing on BD day. Free thyroxine (fT4) levels were within normal limits in all cases except in one case having low fT4 levels with normal TSH levels. No statistically significant changes were encountered between admission thyroid hormone levels and BD-before and BD-day thyroid hormone levels. Six patients were on steroid therapy when BD-before blood samples were drawn, and no difference in thyroid hormone levels was encountered between steroid users and non-users. Correlation analysis showed a positive correlation between GCS and TSH, but a negative association between fT3 and APACHE II. Conclusion: We have shown that patients with BD have altered thyroid hormones days before BD diagnosis, and these alterations continue until the diagnosis of BD. The changes in thyroid hormones are compatible with non-thyroidal illness syndrome.Öğe Anemia and Red Blood Cell Transfusion Practices in a Medical Intensive Care Unit(Soc Turkish Intensivists - Sti, 2022) Akbaş, Türkay; Balbay, Öner AbidinObjective: The study was aimed to describe red blood cell (RBC) transfusion practices in a medical intensive care unit (ICU). Material and Method: This retrospective study involved patients admitted to the ICU between September 2015 and February 2020. A restrictive transfusion strategy was applied during the study period, in which hemoglobin levels were kept between 7.0 and 9.0 g/dL, and the recommended threshold for RBC transfusion was <7 g/dL, except for patients with acute coronary disease, acute cerebrovascular event, heart failure, severe hypoxemia, or undergoing hip fracture surgery, for whom hemoglobin levels were kept at >= 8 g/dL. Results: Six hundred seventeen patients were included in the study (age 70 +/- 16 years, 51.7% male), with a mean hemoglobin level of 11.1 +/- 2.3 g/dL on admission. RBC transfusion was performed on 204 (33.1%) patients, and admission hemoglobin levels were significantly lower in the transfused than the non-transfused patients (9.4 +/- 1.9 vs. 11.9 +/- 2.1 g/dL; p<0.001). An average of 3.5 units per patient was transfused. Transfused patients had high disease severity scores, required high rates of invasive mechanical ventilation, renal replacement therapy and vasopressor use, and had longer ICU and hospital stays. ICU, in-hospital, 28-day, and 90-day mortality rates were significantly high among transfused patients. Logistic regression analysis identified RBC transfusion as an important predictor of 28-day (OR, 2.51; 95% CI, 1.49-4.23, p=0.001) and 90-day (OR, 1.69; 95% CI, 1.25-2.28; p=0.001) mortality. Conclusion: Patients receiving RBC transfusion have high disease severity scores, exhibit low admission hemoglobin levels, require more organ support therapies, and have high mortality rates. The presence of RBC transfusion is a significant predictor of mortality.Öğe Cases of allergic coronary syndrome (Kounis syndrome) : what we should know(Nagoya Univ, Sch Med, 2022) Akbaş, Türkay; Kaya, Adnan; Altun, Gülşah; Esbah, Umit; Önmez, AttilaKounis syndrome (KS) is an acute coronary syndrome that occurs with allergic, hypersensitivity, anaphylactic, or anaphylactoid reactions associated with mast cell activation, and entails significant morbidity and mortality risks. We present four cases of acute coronary syndrome developing after insect bites, chemotherapy, and coronary stent implantation. Two patients were lost due to anaphylactic shock-related multiorgan failures and sudden cardiac death. Since a wide range of drugs, foods, environmental conditions, and disease states may be associated with KS, all physicians must be aware of the syndrome.Öğe A Critically Ill Patient with Aspergillus Fumigatus Sepsis-Related Ischemic Colitis(2022) Coşkun, Gökhan; Torun, Serkan; Akbaş, Türkay; Akin, Gul; Önbaş, ÖmerBackground: Invasive aspergillosis (IA) is an opportunistic infection generally encountered in patients with hematological malignancies. However, IA is increasingly recognized in non-neutropenic and critically ill patients in the absence of classic risk factors. Case Report: An 81-year-old man with diabetes mellitus (DM), chronic renal failure (CRF), and heart failure, who had had 1-week complaints of diarrhea, nausea, and vomiting, was admitted to the intensive care unit with septic shock, acute respi- ratory failure, and acute kidney injury. Chest computed tomography showed cavitary lung lesions and colonoscopy revealed ischemic ulcers in the descending colon. Other causes of cavitary lung lesions were excluded and all cultures were negative, except for bronchoalveolar lavage yielding Aspergillus fumigatus. Thus, Aspergillus fumigatus sepsis with multiorgan failures was diagnosed. Conclusion: Inhaled Aspergillus conidia are kept under control by alveolar macrophage. DM, CRF, and aging are the con- ditions that disrupt phagocytic activity of macrophages and predispose to IA.Öğe A Critically Ill Patient with Aspergillus Fumigatus Sepsis-Related Ischemic Colitis(Erciyes Univ Sch Medicine, 2022) Akbaş, Türkay; Coşkun, Gökhan; Torun, Serkan; Akın, Gül; Önbaş, ÖmerBackground: Invasive aspergillosis (IA) is an opportunistic infection generally encountered in patients with hematological malignancies. However, IA is increasingly recognized in non-neutropenic and critically ill patients in the absence of classic risk factors.Case Report: An 81-year-old man with diabetes mellitus (DM), chronic renal failure (CRF), and heart failure, who had had 1-week complaints of diarrhea, nausea, and vomiting, was admitted to the intensive care unit with septic shock, acute respi-ratory failure, and acute kidney injury. Chest computed tomography showed cavitary lung lesions and colonoscopy revealed ischemic ulcers in the descending colon. Other causes of cavitary lung lesions were excluded and all cultures were negative, except for bronchoalveolar lavage yielding Aspergillus fumigatus. Thus, Aspergillus fumigatus sepsis with multiorgan failures was diagnosed.Conclusion: Inhaled Aspergillus conidia are kept under control by alveolar macrophage. DM, CRF, and aging are the con-ditions that disrupt phagocytic activity of macrophages and predispose to IA.Öğe Etanercept-Induced Thrombocytopenia In A Patient With Ankylosing Spondylitis(DAHUDER, 2022) Önmez, Attlla; Altun, Gulsah; Akbaş, Türkay; Öneç, BirgülTumor necrosis factor-alpha (TNF-?), which is produced by macrophages and activated T lymphocyte cells, plays a main role in inducing further stimulation of other inflammatory cells. Anti-TNF-? drugs are used for induction and preservation of remission in patients with Ankylosing spondylitis. Etanercept, which is one of the most used Anti-TNF-? drugs, has side effects such as cytopenia but isolated thrombocytopenia is an uncommon adverse event. We report the case of a 40-year-old man diagnosed with Ankylosing spondylitis who developed Etanercept-induced isolated thrombocytopenia.Öğe A Five Year Experience of The Tracheostomy Procedure In a Medical Intensive Care Unit(Soc Turkish Intensivists - Sti, 2022) Akbaş, Türkay; Şenocak Taşcı, Elif; Genç, EsraObjective: Tracheostomy formation is one of the most commonly performed surgical procedures in the intensive care unit (ICU). This study aimed to analyze tracheostomy indications, complications and survival rates, and to compare characteristics and outcomes of patients who had undergone surgical tracheostomy (ST) and percutaneous dilational tracheostomy (PDT). Methods: It was a prospective nonrandomized study conducted at a university hospital ICU. It included 88 consecutive adult patients receiving elective tracheostomy between September 2015 and February 2020. Results: The main indications for tracheostomy were prolonged mechanical ventilation, airway protection and pulmonary hygiene. The patients received a tracheostomy after a median of 17 (9-25) days of endotracheal intubation. Twenty-five percent of the patients were mobilized and 27% started oral feeding after tracheostomy. The survival rates at 28 days after tracheostomy, hospital discharge and 1 year were 64.8%, 40.9% and 15.9%, respectively. The ratio of the patients with ST was 36%. There were no differences in demographic data, comorbidity, admission diagnosis, complication rate, tracheostomy indication and survival rate between ST and PDT groups. Although duration of intubation before tracheostomy were similar between the groups, the time passed from informed consent for tracheostomy to the tracheostomy procedure was longer in the ST group (PDT, 3 [1-6]; ST, 6 [2-11] days; p=0.011). All ST patients had preoperative consultations from other clinics and the mean number of consultation per patient was 2.7. Conclusion: Both ST and PDT were safe procedures in the ICU. Since several consultations were requested, the implementation of the procedure was delayed for ST compared to PDT.Öğe High Flow Nasal Oxygen Therapy Usage in the Adult Intensive Care Units in Turkey: Multi-center, Prospective Study(European Respiratory Soc Journals Ltd, 2019) Yıldırım, Fatma Bodur; Öcal, Serpil; Ortaç, Ebru Ersoy; Yöndem, Ömer Zühtü; Yüksel, Barış Ecevit; Akbaş, Türkay; Koşar, Filiz…Öğe İnvazif Kandida Enfeksiyonu(2023) Altun, Gülsah; Akbaş, Türkay; Yekenkurul, DilekYüksek mortalite ve morbidite ile ilişkili olan fungal enfeksiyonların sıklığı giderek artmaktadır. Fungal enfeksiyonlarda en fazla saptanan etkenler kandida türleridir. Kandida enfeksiyonlarında en önemli risk faktörü, deri ve mukozaların kandida türleriyle kolonize olmasıdır. Vasküler ve üriner kateter uygulanması gibi invazif girişimler kolonizasyon ve enfeksiyon riskini arttırmaktadır. İmmunsupresif tedavi alımı, nötrofil ve lenfosit defektleri, fagosit anormallikleri, yoğun bakım ünitesinde yatışı olması, geniş spektrumlu antibiyotik kullanımı, mekanik ventilasyon, parenteral beslenme ve abdominal cerrahi de risk faktörlerindendir. Diğer enfeksiyonlardan ayırt edici semptom veya bulgusunun olmaması, kandida enfeksiyonlarının gözden kaçmasına ve geç tanı konulmasına sebep olmaktadır. Bu nedenle klinik tanı için uygulanabilirliği kolay olan kandidanın kolonize olma indeksi, Ostrosky klinik tahmin kuralı ve kandida skorlaması sistemleri geliştirilmiştir. Kesin tanı için maya veya hif formlarının, kan veya doku kültürlerinde gösterilmesi gerekmektedir. Mortalite riski yüksek olan bu enfeksiyonlarda, erken müdahale ölüm oranını azaltmaktadır. Tedavi yöntemleri profilaktik, ampirik, preempitif ve hedefe yönelik tedavi olmak üzere dört gruba ayrılmaktadır. Fungal enfeksiyon açısından yüksek riskli hastalarda, enfeksiyonun gelişmemesi için uygulanan koruyucu tedavi yöntemi profilaktik tedavidir. Ampirik tedavi, nedeni açıklanamayan ateşi olan ve steril olmayan alanlarda kandida üremesi saptanan hastalarda uygulanan tedavi yöntemidir. Yüksek olası invazif kandidiyazis için şokta olan hastalarda preempitif tedavi uygulanırken, steril ortamlarda kandida invazyonu gösterilen durumlarda hedefe yönelik tedavi verilmektedir.Öğe Long length of stay in the ICU associates with a high erythrocyte transfusion rate in critically ill patients(Sage Publications Ltd, 2019) Akbaş, TürkayObjective This study aimed to evaluate epidemiology and outcome among critically ill patients under a restrictive transfusion practice. Methods One hundred sixty-nine patients who were admitted to the intensive care unit (ICU) between March 2016 to December 2017 and remained in the ICU > 24 hours were retrospectively included. Results Hemoglobin levels on admission were <12 g/dL in 85% and <9 g/dL in 37.9% of patients. The median admission hemoglobin level was decreased on the last day of the ICU stay. Erythrocyte transfusion was required for 34% of patients. Transfused patients had high Acute Physiology and Chronic Health Evaluation II and Sequential Organ Failure Assessment scores, more requirement for invasive mechanical ventilation, vasopressors, and dialysis, long ICU and hospital stays, low hemoglobin levels, and high hospital and ICU mortality rates. Multivariate analysis showed that the likelihood of transfusion increased from 6.6 to 25.8 fold when the ICU stay extended from >= 7 to >= 15 days. Age, vasopressor use, dialysis, and erythrocyte transfusion >= 5 units were predictors of mortality. Conclusion Patients receiving transfusion are severely ill and have more life support therapies. The number of erythrocyte units transfused, age, and organ support therapies are independent predictors of mortality.Öğe Nekrotizan Fasiit: Gecikmiş Cerrahi Müdahale Mortaliteyi Artırır(Düzce Üniversitesi, 2015) Akbaş, Türkay; Bilgin, Hüseyin; Aykut, Umut; Karakurt, SaitNecrotizing fasciitis is a rapidly progressive infection of subcutan and fascia. Urgent surgical intervention should bedone otherwise it can be mortal. Here, we are going to present a case who was internated into the intensive care unit dueto NF-induced multiple organ failure which developed after trauma, and then, we are going to have a discussion aboutNFÖğe Neuroendocrine changes in brain dead patients(Elsevier Science Bv, 2017) Akbaş, Türkay; Öztürk, Ayhan…Öğe Nöroloji Yoğun Bakım Ünitesinde Beyin Ölümü Tanısı Konulan Olguların İncelenmesi(2018) Akbaş, Türkay; Kurtpınar, Zeynep; Şenadım, Songül; Çoban, Eda; Özkubat, Vildan; Bayrak, Sünkar Kaya; Ataklı, DilekAmaç: Ülkemizde kadavradan organ naklinin düşük olmasının önemli nedeni yoğun bakım ünitelerinde (YBÜ) çalışan klinisyenlerinbeyin ölümü (BÖ) tanısını koymaya odaklanmamasıdır. Bu çalışmada nöroloji yoğun bakım ünitesinde BÖ tanısı konulanvakaların incelenmesi planlanmıştır.Hastalar ve Yöntem: Bu çalışmada Bakırköy Ruh Sinir Hastalıkları Eğitim ve Araştırma Hastanesi nöroloji YBÜ’de bir yıl içinde BÖtanısı konmuş 23 erişkin vaka retrospektif olarak değerlendirilmiştir.Bulgular: Vakalarımızın %56.3’ü erkek olup, yaş ortalaması 6214 sene olarak bulunmuş, yatış tanıları iskemik inme (%52.2),intrakranial kanama (%39.2), sinüs trombozu (%4.3) ve hipoksik ensefalopati (%4.3) idi. YBÜ’ye alındıktan sonra BÖ tanısı konulmasınakadar geçen süre 27.5 (10.6-135) saat bulunmuştur. BÖ tanısını düşündüren klinik bulgular, beyin sapı arefleksisi,Glasgow koma skor düşüklüğü, spontan solunum kaybı ve poliüridir. BÖ tanısı 13 vakada YBÜ uzmanı ile anestezi ve reanimasyonuzmanı tarafından, 10 hastada ise nöroloji uzmanı tarafından ilk olarak düşünülüp tanı işlemlerine gidilmiştir. BÖ tanısı 15olguda apne testi ve nörolojik muayeneyle konulmuştur. Beş olguda apne testinin yapılamaması ve üç olguda tanıyı desteklemekiçin ek testler yardımıyla tanıya gidilmiştir. Vakaların %95.5’inde hipotansiyon, %78’inde diabetes insipidus ve %61.9’undahipotermi gelişmiş ve uygun tedavileri yapılmıştır. Olgularımızın %13’ü donör olmuştur.Sonuç: YBÜ’de vaka takibi yapan doktor ve hemşirelerin beyin ölümünü tanıma ve donör bakımı konusunda eğitimli olması ileBÖ tanısının konulması oranı ve bunun sonucunda kadavradan organ nakli sayısı artacaktır.Öğe Pankreatik Nöroendokrin Karsinomda Paraneoplastik Ciddi Sensorimotor Aksonal Polinöropati: Vaka Sunumu ve Literatür Taraması(2022) Akbaş, Türkay; Kantarcıoğlu Coşkun, Sinem; Torun, Serkan; Öztürk, Ayhan; Eşbah, Onur; Onbas, OmerAmaç: Paraneoplastik nörolojik sendromlar (PNSs), kanser öncesi veya kanser sırasında gelişen, sinir sisteminin herhangi bir kısmını etkileyen çeşitli nörolojik hastalıkları içermektedir. Vaka: Yetmiş sekiz yaşında erkek hastanın üç yıl önce üst ekstremitelerde ağrı ve yanma hissi şikayetleri başlamış ve kısa süre sonra kas güçsüzlüğü eklenmiş. Bir yıl önce de alt ekstremitelerde benzer şikayetler ortaya çıkmış. Yoğun bakım ünitesine pnömoni tansıyla yatırılan hastanın yatış esnasında bilinci açık, fakat kuadriplejik ve modifiye Rankin skoru 5 idi. Abdomen bilgisayarlı tomografi karaciğer ve pankreasta kitle lezyonlarının olduğunu gösterdi. Lezyonyonlardan alınan biyopsiler pankreas orjinli küçük hücreli nöroendokrin karsinom olarak raporlandı. Elektrofizyolojik testler ciddi sensorimotor aksonal polinöropati ile uyumluluk gösteriyordu Diğer polinöropati nedenleri dışlandıktan sonra, hastaya paraneoplastik sensorimotor aksonal polinöropati tanısı konuldu. Hastanın fonksiyonel kapasitesi düşük olduğundan palyatif tedavi planlandı. Sonuç: PNS’li hastalarda uygun tedavinin başlanması için erken kanser tanısının konulması önem arz etmektedir.Öğe Paraneoplastic Severe Sensorimotor Axonal Polyneuropathy in Pancreatic Neuroendocrine Carcinoma: A Case Report and Review of the Literature(Duzce Univ, Fac Medicine, 2022) Akbaş, Türkay; Coşkun, Sinem Kantarcıoğlu; Torun, Serkan; Öztürk, Ayhan; Esbah, Onur; Önbaş, ÖmerObjective: Paraneoplastic neurological syndromes (PNSs) are a diverse group of neurological disorders affecting any part of the nervous system before or during cancer. Case: A 78-year-old man first experienced pain and burning in the upper extremity three years previously, to which muscle weakness was added a short time later. The same symptoms developed in the lower extremities one year previously. He was admitted to the intensive care unit due to pneumonia and was conscious but quadriplegic with a modified Rankin score of 5. Abdominal computed tomography showed mass lesions in the liver and pancreas. Biopsies revealed pancreatic small cell neuroendocrine carcinoma. Electrophysiological studies revealed severe sensorimotor axonal polyneuropathy. Paraneoplastic sensorimotor axonal polyneuropathy was diagnosed since other causes of polyneuropathy had been excluded. Palliative care was considered due to the patient's poor functional state. Conclusions: Early diagnosis of cancer is of paramount importance in patients with PNSs if appropriate treatment is to be provided.Öğe The pituitary-gonadal-thyroid and lactotroph axes in critically ill patients(Via Medica, 2016) Akbaş, Türkay; Deyneli, Oğuzhan; Sönmez, Firuze Turan; Akalın, SemaIntroduction: The normal circadian rhythm of hormones in critical patients becomes chaotic causing some hormones to increase and others to decrease abnormally. The goal of this study is to evaluate hormonal changes in severely ill patients and to investigate the relationship between hormonal changes and mortality and morbidity. Material and methods: We enrolled 20 patients (10 F/10 M). Blood samples were collected on day 0, day 5, and day 10. If a patient was discharged before these defined days, a sample was drawn on that day. Twenty healthy controls were included. Results: Female patients had lower LH, FSH, and fT(3) and higher PRL and cortisol levels than controls on admission to the intensive care unit (ICU) (p(LH) = 0.021, p(FsH):0.001, p(f13) = 0.021, p(PRL) = 0.042, p(Cortisol) < 0.001, respectively). Men had significantly low testosterone and fT(3), and high PRL and cortisol levels on ICU admission (p(T) = 0.01, p(fT3) = 0.043, p(PRL) = 0.005, p(Cortisol) < 0.001, respectively). The lowest levels of gonadotropins in both genders and testosterone in men were measured on day 5. Cortisol levels decreased in the patients discharged from the ICU (p = 0.01). FSH levels increased in recovered women (p(FSH) = 0.043). The mortality rate was 30%. There were correlations between admission TSH and NIMV duration (p = 0.006), fT(3) and APACHE II (p = 0.001), and PRL and mortality (p = 0.044). Positive correlations between E-2 and APACHE II (p = 0.003) in females, and PRL and APACHE II (p = 0.022) in males were also displayed. Conclusions: Critically ill patients develop significant changes in neuroendocrine axes. Alterations in hormones correlate with the disease severity and mortality.Öğe Severe Acidemia, Leukocytosis and Low Hematocrit Levels at Admission as Mortality Predictors of Elderly Intensive Care Unit Patients(Turkish Soc Medical & Surgical Intensive Care Medicine, 2019) Akbaş, Türkay; Taşçı, Elif Şenocak; Yılmaztepe, Hafize Titiz; Sönmez, Feruze Turan; Köş, Durdu Mehmet; Öneç, BirgülAim: Rapid prediction of prognosis is helpful in reflecting the disease severity and patient mortality. This is especially important in critically ill elderly patients who have high mortality risk. This study aimed to investigate the effects of admission laboratory results and medical histories on the prediction of prognosis in critically ill elderly patients. Material and Methods: Patients who were >= 65 years and admitted to a medical intensive care unit (ICU) between 2011 and 2013 were retrospectively analyzed. Results: The study included 449 patients and mortality rate was 47.4%. Nonsurvivors had lower pH, HCO3 and albumin levels, and lower hematocrit and platelet counts, but higher aspartate aminotransferase, alanine aminotransferase, C-reactive protein (CRP), creatinine, phosphorus, magnesium and bilirubin levels, and higher leukocyte count than survivors. The rates of chronic kidney disease, being in a bedridden state and having cardiopulmonary resuscitation (CPR) before ICU admission were significantly high in nonsurvivors. Multivariate analysis showed that pH <7.20, albumin <= 2 gr/dL, low hematocrit and high CRP levels, high leukocyte count, bedridden state, and CPR were mortality predictors. After including the admission diagnoses and endotracheal intubation into the model, pH <7.20 (odds ratio [OR], 4.31; 95% confidence interval [CI], 1.59-11.70), albumin <= 2 gr/dL (OR, 3.61; 95% CI, 0.99-13.03), hematocrit level (OR, 0.94; 95% CI, 0.91-0.99) and leukocyte count (OR 1.06; 95% CI, 1.01-1.11) retained their prognostic importance for mortality. Conclusions: Severe acidemia, low albumin and hematocrit levels, and high leukocyte count at admission help clinicians to foresee the prognosis in severely ill elderly patients. They keep their importance even in the presence of other fundamental mortality predictors.Öğe Sjögren’s syndrome and catastrophic antiphospholipid syndrome with severe skin involvement(2020) Karagün, Ebru; Öneç, Birgül; Akbaş, Türkay; Gamsızkan, MehmetCatastrophic antiphospholipid syndrome is a rare butrapidly progressing form of antiphospholipid antibodysyndrome with high mortality. The syndrome causesmultiorgan failure associated with diffuse microthromboses. Necrotic-appearing ecchymotic lesionsemerging from the distal aspect of both lower extremitiesand progressing to the upper leg region, and to the upperextremities developed in a 58-year-old woman.Histopathological examination of the biopsy specimenrevealed intravascular microthrombi in the dermis.Laboratory findings for anti-cardiolipin antibodies IgMand lupus anticoagulant resulted positive. Lung and kidneyinvolvement was observed. The clinical course progressedvery quickly, and catastrophic antiphospholipid syndromewas diagnosed with these findings. Two-thirds ofcatastrophic antiphospholipid syndrome cases developdue to secondary causes, the most common beinginfections. Catastrophic antiphospholipid syndrome mayalso accompany autoimmune diseases, particularlysystemic lupus erythematosus. This report is presented toemphasize that Sjögren's syndrome should be consideredin the etiology of catastrophic antiphospholipid syndromeÖğe Thrombocytopenia was an Indicator of Severity of Disease in Critically Ill Patients(Duzce University, 2025) Akbaş, TürkayAim: Thrombocytopenia is frequently encountered in critically ill patients. The study aimed to determine the frequency of thrombocytopenia, and the relationship between thrombocytopenia and morbidity and mortality in patients admitted to the tertiary medical intensive care unit (ICU). Material and Methods: This retrospective study included 681 patients admitted to the ICU between March 2018 and February 2020. Hospitalization diagnosis, comorbidities, admission laboratory tests, acute physiology and chronic health evaluation (APACHE) II and sequential organ failure assessment (SOFA) scores, organ support therapies and mortality were recorded. Thrombocytopenia was defined as a platelet count ofÖğe Thyroid Hormone Levels in Brain Death Patients(Lippincott Williams & Wilkins, 2017) Akbaş, Türkay; Öztürk, Ayhan; Şahin, İbrahim Ethem…
