Closed-Loop Nonlinear Adaptive Control of Anti-angiogenic Tumor Therapy
| dc.contributor.author | Hasırcı, Uğur | |
| dc.contributor.author | Burg, Timothy C. | |
| dc.contributor.author | Groff, Richard E. | |
| dc.date.accessioned | 2020-04-30T22:40:55Z | |
| dc.date.available | 2020-04-30T22:40:55Z | |
| dc.date.issued | 2013 | |
| dc.department | DÜ, Mühendislik Fakültesi, Elektrik-Elektronik Mühendisliği Bölümü | en_US |
| dc.description | 9th Asian Control Conference (ASCC) -- JUN 23-26, 2013 -- Istanbul, TURKEY | en_US |
| dc.description | WOS: 000333734900328 | en_US |
| dc.description.abstract | A nonlinear adaptive backstepping controller for the anti-angiogenic tumor growth control problem is presented. The proposed control algorithm directly aims to drive the tumor volume along a desired trajectory as part of a treatment regimen. Toward this aim, we first present an exact-model knowledge controller that ensures the exponential tracking of a time-varying tumor volume profile, and then, an adaptive controller is shown that provides asymptotic tracking despite model uncertainties. A Lyapunov-based analysis approach is used to determine stability and performance results. Numerical simulation results are presented to demonstrate the performance of the proposed approach. Finally, the requirements of a real-time implementation of an in-vitro model of the overall system are discussed. | en_US |
| dc.identifier.isbn | 978-1-4673-5769-2; 978-1-4673-5767-8 | |
| dc.identifier.issn | 2072-5639 | |
| dc.identifier.uri | https://hdl.handle.net/20.500.12684/3087 | |
| dc.identifier.wosquality | N/A | en_US |
| dc.indekslendigikaynak | Web of Science | en_US |
| dc.language.iso | en | en_US |
| dc.publisher | Ieee | en_US |
| dc.relation.ispartof | 2013 9Th Asian Control Conference (Ascc) | en_US |
| dc.relation.ispartofseries | Asian Control Conference ASCC | |
| dc.relation.publicationcategory | Konferans Öğesi - Uluslararası - Kurum Öğretim Elemanı | en_US |
| dc.rights | info:eu-repo/semantics/closedAccess | en_US |
| dc.title | Closed-Loop Nonlinear Adaptive Control of Anti-angiogenic Tumor Therapy | en_US |
| dc.type | Conference Object | en_US |
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