A traditional herbal remedy in liver diseases: Momordica charantia L. (kudret narı/bitter melon)

dc.contributor.authorGunduz, Dudu Altintas
dc.contributor.authorBalaban, Yasemin
dc.contributor.authorCaliskan, Ufuk Koca
dc.date.accessioned2026-07-01T11:36:28Z
dc.date.available2026-07-01T11:36:28Z
dc.date.issued2026
dc.departmentDüzce Üniversitesi
dc.description.abstractThe liver is the central organ regulating the body’s metabolism; therefore, liver diseases negatively affect metabolic activities as well as the immune system. Momordica charantia L. is one of the medicinal plants used in folk medicine to prevent or treat liver diseases. M. charantia contains compounds with antioxidant and anti-inflammatory properties that protect liver cells from free radical damage and reduce inflammation. In addition, the phytochemicals of M. charantia may help regulate blood sugar levels, thereby supporting metabolism and reducing fat accumulation in the liver. Previous studies indicate that M. charantia has the potential to enhance liver function while reducing the incidence of fatty liver disease. This study aimed to summarize data from in vivo studies investigating the hepatoprotective mechanisms of M. charantia at various application doses, highlighting its potential as a future dietary supplement candidate. However, due to insufficient evidence regarding its safety, the possibility of hepatotoxic effects should not be disregarded. © 2026, Kare Publishing. All rights reserved.
dc.identifier.doi10.14744/hf.2025.98035
dc.identifier.endpage162
dc.identifier.issn2757-7392
dc.identifier.issue2
dc.identifier.scopus2-s2.0-105041804688
dc.identifier.scopusqualityQ3
dc.identifier.startpage154
dc.identifier.urihttps://doi.org/10.14744/hf.2025.98035
dc.identifier.urihttps://hdl.handle.net/20.500.12684/23061
dc.identifier.volume7
dc.indekslendigikaynakScopus
dc.language.isoen
dc.publisherKare Publishing
dc.relation.ispartofHepatology Forum
dc.relation.publicationcategoryDiğer
dc.rightsinfo:eu-repo/semantics/openAccess
dc.snmzKA_Scopus_20260623
dc.subjectBitter melon
dc.subjecthepatoprotective effect
dc.subjectliver diseases
dc.subjectMomordica charantia
dc.subjectnon-alcoholic fatty liver disease (NAFLD)
dc.titleA traditional herbal remedy in liver diseases: Momordica charantia L. (kudret narı/bitter melon)
dc.typeReview

Dosyalar