Obezite polikliniğine başvuran hastalarda hematolojik parametreler ile kardiyovasküler risk skorlamasının karşılaştırmalı değerlendirilmesi
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Tarih
2022
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Düzce Üniversitesi
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info:eu-repo/semantics/openAccess
Özet
Amaç: Bu çalışmada, obezite polikliniğine başvuran hastalarda; hematolojik ve biyokimyasal parametreler ile kardiyovasküler risk skorlamasının karşılaştırmalı değerlendirilmesi amaçlanmıştır. Yöntem: Tanımlayıcı-kesitsel olarak planlanan bu araştırmada, Düzce Üniversitesi Araştırma ve Uygulama Hastanesinin Obezite Polikliniğine 2017-2018 yılları arasında başvuran hastaların, dosya verileri retrospektif olarak değerlendirildi. Hastaların yaş, cinsiyet, sigara kullanımları, DM tanılarının varlığı, BKİ değerleri kaydedildi; kardiyovasküler risk faktörleri Avrupa ve Türkiye Kardiyoloji Dernekleri risk skorlamasına göre değerlendirildi. Bulgular: Çalışmaya %75,1'i kadın, %24,9'u erkek, 631 katılımcı dahil edilmiştir. Yaş ortalaması 38,9±12,1 (min=21-maks=65) olarak bulunmuştur. Hastaların %19,2'sinin sigara kullandığı, %4,6'sında DM ve %36,9'unda insülin direnci olduğu görülmüştür. Katılımcıların %3,3'ü zayıf, %7,3'ü normal kilolu, %22,5'i fazla kilolu ve %66,9'u obezdir. Türkiye Kardiyoloji Derneği risk skorlamasına göre hastaların %51,4'i düşük , %20,5'i orta ve %28,1'i yüksek risklidir. Avrupa Kardiyoloji Derneği risk skorlamasına göre ise hastaların %83,5'i düşük, %10,9'u orta ve %5,5'i yüksek risklidir. Her iki risk skorlamasına göre risk grupları arasında yaş, cinsiyet, beden kitle indeksi ve DM varlığı açısından anlamlı farklılık görüldü (p<0,001). Türkiye Kardiyoloji Derneği risk skorlamasına göre; düşük risk grubunda olanların daha yüksek trombosit/lenfosit oranına ve daha düşük total kolesterol/HDL oranına sahip olduğu görüldü. Her iki skorda da kardiyovasküler risk ile RDW, MPV, lökosit sayısı, nötrofil/lenfosit oranı değerlerinde ilişki saptanmadı. Sonuç: Birinci basamak sağlık hizmetlerine obezite danışmanlığı için başvuran hastalara risk değerlendirmesi yapılması önemlidir. Yapılan kardiyovasküler risk değerlendirmesi ile bazı önlemlerin erkenden alınması sağlanabilir. Riskin erken saptanması amacıyla klinisyenlerin kolay ulaşabilecekleri parametreleri ortaya çıkaracak daha çok çalışmaya ihtiyaç vardır. Anahtar Kelimeler: Obezite, BKİ, trombosit/lenfosit oranı, kardiyovasküler risk skoru, hematolojik parametreler
Objective: In this study, it was aimed to compare hematological- biochemical parameters and cardiovascular risk scoring in patients applied to obesity outpatient clinic. Method: In this descriptive cross-sectional study, data of the patients who applied to the Obesity Outpatient Clinic of Duzce University Research and Application Hospital between 2017 and 2018 were evaluated retrospectively. Age, gender, smoking status, presence of Diabetes Mellitus (DM) and body mass indexes of the patients included in the study were noted; cardiovascular risk of the patients were calculated using scoring system of the European and Turkish cardiology societies (ESC, TSC). Results: 631 participants; 75.1% female and 24.9% male, were included in the study. The mean age of the patients was found to be 38.9±12.1 (min=21, max=65). It was observed that 19.2% of the patients were smokers, 4.6% had DM and 36.9% had insulin resistance. Among the participants; 3.3% of the patients were underweight, 7.3% were normal weight, 22.5% were overweight and 66.9% were obese. According to TSC risk scoring system, 51.4% of the patients were in low risk, 20.5% medium risk and 28.1% high risk categories. According to the ESC risk scoring system, 83.5% of the patients were in low risk, 10.9% medium risk and 5.5% high risk categories. According to both risk scoring systems, there was a significant difference between the risk groups in terms of age, gender, BMI and presence of DM (p<0.001). According to TSC risk score; It was observed that those in the low risk group had a higher platelet/lymphocyte ratio and a lower total cholesterol/HDL ratio. In both scores, there was no correlation found between cardiovascular risk and RDW, MPV, leukocyte count and NLR(Neutrophil-Lymphocte ratio). Conclusion: It is of importance to conduct a risk assessment for patients who apply to primary health care services for obesity counseling. With the cardiovascular risk assessment, some precautions can be taken early. More studies are needed to reveal easily accessible parameters which can predict the cardiovascular risk. Keywords: Obesity, BMI, platelet to lymphocyte ratio, cardiovascular risk scores, hematological parameters
Objective: In this study, it was aimed to compare hematological- biochemical parameters and cardiovascular risk scoring in patients applied to obesity outpatient clinic. Method: In this descriptive cross-sectional study, data of the patients who applied to the Obesity Outpatient Clinic of Duzce University Research and Application Hospital between 2017 and 2018 were evaluated retrospectively. Age, gender, smoking status, presence of Diabetes Mellitus (DM) and body mass indexes of the patients included in the study were noted; cardiovascular risk of the patients were calculated using scoring system of the European and Turkish cardiology societies (ESC, TSC). Results: 631 participants; 75.1% female and 24.9% male, were included in the study. The mean age of the patients was found to be 38.9±12.1 (min=21, max=65). It was observed that 19.2% of the patients were smokers, 4.6% had DM and 36.9% had insulin resistance. Among the participants; 3.3% of the patients were underweight, 7.3% were normal weight, 22.5% were overweight and 66.9% were obese. According to TSC risk scoring system, 51.4% of the patients were in low risk, 20.5% medium risk and 28.1% high risk categories. According to the ESC risk scoring system, 83.5% of the patients were in low risk, 10.9% medium risk and 5.5% high risk categories. According to both risk scoring systems, there was a significant difference between the risk groups in terms of age, gender, BMI and presence of DM (p<0.001). According to TSC risk score; It was observed that those in the low risk group had a higher platelet/lymphocyte ratio and a lower total cholesterol/HDL ratio. In both scores, there was no correlation found between cardiovascular risk and RDW, MPV, leukocyte count and NLR(Neutrophil-Lymphocte ratio). Conclusion: It is of importance to conduct a risk assessment for patients who apply to primary health care services for obesity counseling. With the cardiovascular risk assessment, some precautions can be taken early. More studies are needed to reveal easily accessible parameters which can predict the cardiovascular risk. Keywords: Obesity, BMI, platelet to lymphocyte ratio, cardiovascular risk scores, hematological parameters
Açıklama
Anahtar Kelimeler
Obezite, BKİ, trombosit/lenfosit oranı, kardiyovasküler risk skoru, hematolojik parametreler, Obesity, BMI, platelet to lymphocyte ratio, cardiovascular risk scores, hematological parameters, Aile Hekimliği, Family Medicine
