The effects of different fatty acids on nesfatin-1, omentin-1, adropin, leptin and ghrelin levels

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dc.contributor.authorBeyazçıçek, Ersın
dc.contributor.authorSahin, Seda
dc.date.accessioned2026-07-01T11:34:05Z
dc.date.available2026-07-01T11:34:05Z
dc.date.issued2023
dc.departmentDüzce Üniversitesi
dc.description.abstractThere are many studies on nesfatin-1, omentin, adropin, leptin, and ghrelin. However, data on the effects of long, medium, and short chain fatty acids on serum/ tissue concentrations of nesfatin-1, omentin, adropin, leptin, and ghrelin are scarce. This study aims to investigate the effects of butyric acid, caprylic acid, and oleic acid alone or in combination on nesfatin-1, omentin, adropin, leptin, and ghrelin secretion. In the study, 49 male Wistar rats were used. The rats were randomly divided into 7 groups as control (CONT), butyric acid (BA), caprylic acid (CA), oleic acid (OA), butyric acid+caprylic acid (BA+CA), butyric acid+oleic acid (BA+OA) and caprylic acid+oleic acid (CA+OA) groups. The rats were orally administered fatty acids for twenty-one days. At the end of the study, the levels of nesfatin-1, omentin, adropin, leptin, and ghrelin were determined by the ELISA method. When the groups were compared in terms of nesfatin-1, omentin, adropin, leptin, and ghrelin levels, the butyric acid group had higher nesfatin-1, omentin, adropin, leptin, and ghrelin levels than the other groups (p<0.05). No statistically significant difference was found in the other groups (p>0.05). In conclusion, it was observed that butyric acid use caused an increase in serum nesfatin-1, omentin, adropin, leptin, and ghrelin levels.
dc.identifier.doi10.5455/medscience.2023.08.168
dc.identifier.endpage1123
dc.identifier.issn2147-0634
dc.identifier.issue4
dc.identifier.startpage1117
dc.identifier.trdizinid1261261
dc.identifier.urihttps://doi.org/10.5455/medscience.2023.08.168
dc.identifier.urihttps://search.trdizin.gov.tr/tr/yayin/detay/1261261
dc.identifier.urihttps://hdl.handle.net/20.500.12684/22940
dc.identifier.volume12
dc.indekslendigikaynakTR-Dizin
dc.language.isoen
dc.relation.ispartofMedicine Science
dc.relation.publicationcategoryMakale - Ulusal Hakemli Dergi - Kurum Öğretim Elemanı
dc.rightsinfo:eu-repo/semantics/openAccess
dc.snmzKA_TR_20260623
dc.subjectBiyoloji
dc.titleThe effects of different fatty acids on nesfatin-1, omentin-1, adropin, leptin and ghrelin levels
dc.typeArticle

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