Systemic Investigation of Acute Toxicity of Some Food Supplements on The Market in Turkey

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dc.contributor.authorYaşar, Mustafa
dc.contributor.authorŞenoğul, Oğuzhan
dc.contributor.authorGök, Ali
dc.contributor.authorAğan, Kağan
dc.contributor.authorAğan, Aydan Fülden
dc.contributor.authorBeyazçiçek, Ersin
dc.contributor.authorKantarcıoğlu Coşkun, Sinem
dc.date.accessioned2024-12-28T20:24:23Z
dc.date.available2024-12-28T20:24:23Z
dc.date.issued2020
dc.description.abstractObjective: Along with changing living and working conditions in recent years, changes have occurred in eating habits. People are turning to supplements for many purposes such as supplementing normal nutrition, feeling more energetic, enhancing the immune system by taking vitamins and minerals that they think they do not get enough, and meeting their body's needs when they cannot eat a balanced and healthy diet. Supplements are prepared in various forms using nutrients such as vitamins, minerals, proteins, amino acids, plants, enzymes, fiber and fatty acids. These supplement foods are not intended to treat or prevent any disease. In general, supplement foods; it is not a substitute for natural nutrition, but it is intended to complement its deficiencies. They cannot be recommended and sold instead of medicines. Because of many of these products have natural content, they can be placed on the market without toxicity tests. In the current study, it is planned to observe the effects of acute systemic toxicity of supplements that are used in remember regeneration therapy method (RTM) and sold in the markets with the brands’ name of IST-ARD®, ARD-REM®, DVD-ARD®, KT-REM®, ARDZ-REM®, IST-GLIO®, IST-REM®, ROMX®, and REGULIN®. Material-Method: In the experimental design, there were 10 groups (1 control and 9 application groups) male mice. To observe acute toxicity, clinical observation was performed for 72 hours and the biochemical and histopathological parameters of the animals were evaluated at the end of the application. Results: According to the results obtained from the study, there were not found significant differences in biochemical and histopathological evaluations between the control and the application groups. Conclusion: The acute toxicity effect of the food supplements was not determined. May be further studies with bigger numbers of samples investigating the nephrotoxic effects of these products lighten this matter.
dc.identifier.dergiparkDergiPark: 720702
dc.identifier.endpage11
dc.identifier.issn2717-7491
dc.identifier.issue1
dc.identifier.startpage1
dc.identifier.urihttps://dergipark.org.tr/tr/download/article-file/1084734
dc.identifier.urihttps://dergipark.org.tr/tr/pub/ijtcmr/issue/54149/720702
dc.identifier.urihttps://hdl.handle.net/20.500.12684/17227
dc.identifier.volume1
dc.language.isoen
dc.publisherDüzce Üniversitesi
dc.relation.ispartofInternational Journal of Traditional and Complementary Medicine Research
dc.relation.publicationcategoryMakale - Ulusal Hakemli Dergi
dc.rightsinfo:eu-repo/semantics/openAccess
dc.snmzKA_20241228
dc.subjectAcute toxicity
dc.subjectmice
dc.subjectsupplement foods
dc.subjectTraditional, Complementary and Integrative Medicine
dc.titleSystemic Investigation of Acute Toxicity of Some Food Supplements on The Market in Turkey
dc.typeArticle

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International Journal of Traditional and Complementary Medicine Research