Cytotoxicity of Some Retail Food Supplements

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dc.contributor.authorAğyar Yoldaş, Pınar
dc.contributor.authorYoldaş, Taner
dc.contributor.authorSipahi, Nisa
dc.date.accessioned2024-12-28T20:24:16Z
dc.date.available2024-12-28T20:24:16Z
dc.date.issued2020
dc.description.abstractObjective: Medicinal plants and products obtained from medicinal plants are widely used in the treatment of various diseases in our country as well as all over the world. However, scientific data on the biological effects and mechanisms of action of most extracts from medicinal plants are still lacking. Because of that interest in scientific research of the biological effects of medicinal plants and products obtained from medicinal plants is increasing day by day. In addition, the reliability of these products in terms of use apart from their effectiveness is very important for public health. In this study, we aimed to investigate the cytotoxicity of commercially marketed AYM-net® natural herbal food supplements in L929 (mouse fibroblast) cells.Material-Method: In this study, the WST-1 cell proliferation test protocol was applied to examine the cytotoxicity of 19 different products on the market belonging to AYM-net® in L929 cell lines and the results were evaluated according to Elisa microplate reading data. The products were also tested at concentrations of 0.02, 0.03, 0.04, 0.05, 0.06 µg / ml, taking into account the amounts of daily use.Results: When the results were evaluated, 19 different AYM-net® food supplement products sold on the market were cytotoxic in the L929 cell line, in the concentration range of 0.02-0.06 µg/mL, it was observed that the products were not toxic at these dosesConclusion: As a result, different doses of AYM-net® herbal products did not show toxicity on L929 cells. Doses used are within the reliable range.Keywords: L929, cell culture, cytotoxicity, food supplement, herbal mixture
dc.identifier.dergiparkDergiPark: 825544
dc.identifier.endpage136
dc.identifier.issn2717-7491
dc.identifier.issue3
dc.identifier.startpage131
dc.identifier.urihttps://dergipark.org.tr/tr/download/article-file/1395784
dc.identifier.urihttps://dergipark.org.tr/tr/pub/ijtcmr/issue/58250/825544
dc.identifier.urihttps://hdl.handle.net/20.500.12684/17170
dc.identifier.volume1
dc.language.isoen
dc.publisherDüzce Üniversitesi
dc.relation.ispartofInternational Journal of Traditional and Complementary Medicine Research
dc.relation.publicationcategoryMakale - Ulusal Hakemli Dergi
dc.rightsinfo:eu-repo/semantics/openAccess
dc.snmzKA_20241228
dc.subjectL929
dc.subjectCELL CULTURE
dc.subjectCYTOTOXİCİTY
dc.subjectFOOD SUPPLEMENT
dc.subjectHERBAL MİXTURE
dc.subjectTraditional, Complementary and Integrative Medicine
dc.titleCytotoxicity of Some Retail Food Supplements
dc.typeArticle

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International Journal of Traditional and Complementary Medicine Research