Synthesis and characterization of Au and Bi2O3 decorated Fe3O4@PAMAM dendrimer nanocomposites for medical applications
Yükleniyor...
Dosyalar
Tarih
2021
Dergi Başlığı
Dergi ISSN
Cilt Başlığı
Yayıncı
Springer Heidelberg
Erişim Hakkı
info:eu-repo/semantics/closedAccess
Özet
Fe3O4 magnetic nanoparticles were produced and covered with TEOS and APTES which were known to reduce the toxic properties of nanoparticles. Nanoparticles were functionalized second-generation PAMAM dendrimers and doped with Au and Bi2O3 nanoparticles where Fe3O4@G2/Au/Bi2O3 nanocomposites were obtained for potential multimodal imaging applications. Physicals structures of the nanocomposites were characterized using SEM and TEM which illustrate that nanoparticles were in composite form. Chemical composition of nanostructures was confirmed using EDX and FTIR. Magnetic characteristics were checked using VSM. It was seen that nanoparticles have superparamagnetic properties which indicate that nanocomposites have potential to be used in MRI and magnetic hyperthermia applications. X-ray imaging properties were confirmed using X-ray imaging and CT imaging. It was confirmed that doping nanoparticles with Au and Bi2O3 nanoparticles significantly enhanced the X-ray tomography contrast enhancement properties which illustrate the theranostic properties of the nanocomposites.
Açıklama
Anahtar Kelimeler
Fe3O4, Magnetic nanoparticles, PAMAM dendrimers, TEOS, Au, Bi2O3, Medical applications, X-ray tomography
Kaynak
Journal Of Nanostructure In Chemistry
WoS Q DeÄŸeri
Q1
Scopus Q DeÄŸeri
Cilt
11
Sayı
4
