Assessment of the relationship between aortic pulse wave velocity and aortic arch calcification
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Tarih
2012
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info:eu-repo/semantics/openAccess
Özet
Amaç: Semptomlu aterosklerotik hastalığı olmayan hastalarda arteryel sertlik parametreleri ile aort kalsifikasyonu arasındaki ilişkiyi incelemeyi amaçladık. Çalışma planı: Çalışma popülasyonu göğüs grafisinde aort yayı kalsifikasyonu olan 41 hasta (grup I, 17 erkek, ortalama yaş 705 yıl) ve kalsifikasyonu olmayan yaş ve cinsiyet eşleştirilmiş 41 kişiden (grup II, 17 erkek, ortalama yaş 686 yıl) oluşturuldu. Semptomlu veya bilinen vasküler hastalığı olanlar çalışmadan dışlandı. Tüm bireylerin arteryel sertlik parametreleri SphygmoCor cihazı ile ölçüldü. Aort nabzı dalga hızı (PWV), augmentasyon basıncı (AP), augmentasyon indeksi (AIx) ve kalp hızına göre düzeltilmiş augmentasyon indeksi (AIx@75) arteryel sertlik parametreleri olarak değerlendirildi. Bulgular: İki grup demografik özellikler, ilaç kullanımı ve serum lipit düzeyleri açısından karşılaştırıldı, gruplar arasında anlamlı fark yoktu. AP grup Ide grup IIye göre anlamlı olarak yüksek bulundu (p0.002). AIx ve AIx@75 gruplar arası benzerdi. Aort PWVsi grup I de grup IIye göre anlamlı olarak yüksek bulundu (p0.0001). Sonuç: Bu çalışmanın bulgularına göre göğüs grafisinde tespit edilen aort yayı kalsifikasyonu artmış aort nabzı dalga hızı ile ilişkilidir.
Objectives: We aimed to assess arterial stiffness parameters and to investigate the relationship between these parameters and aortic calcification in patients with aortic arch calcification and without symptomatic atherosclerotic disease. Study design: The population of this study consisted of 41 patients with aortic arch calcification verified by chest X-ray (group I, 17 males, mean age 70±5 years) and individuals without aortic arch calcification (group II, 17 males, mean age 68±6 years). Subjects with symptomatic or known vascular disease were excluded from the study. The arterial stiffness parameters of all subjects were measured noninvasively with a SphygmoCor device. Aortic pulse wave velocity (PWV), augmentation pressure (AP), augmentation index (AIx) and heart rate normalized augmentation index (AIx@75) were used as parameters of arterial stiffness. Results: The two groups were compared according to demographic characteristics, medications currently being taken, and levels of serum lipids. There was no significant difference between the groups. AP in group I was significantly higher than that of group II (p0.002). AIx and AIx@75 were similar in both groups. Aortic PWV of group I was significantly higher than that of group II (p<0.0001). Conclusion: According to the results of this study, the presence of aortic calcification, verified by chest radiography, was associated with increased aortic PWV.
Objectives: We aimed to assess arterial stiffness parameters and to investigate the relationship between these parameters and aortic calcification in patients with aortic arch calcification and without symptomatic atherosclerotic disease. Study design: The population of this study consisted of 41 patients with aortic arch calcification verified by chest X-ray (group I, 17 males, mean age 70±5 years) and individuals without aortic arch calcification (group II, 17 males, mean age 68±6 years). Subjects with symptomatic or known vascular disease were excluded from the study. The arterial stiffness parameters of all subjects were measured noninvasively with a SphygmoCor device. Aortic pulse wave velocity (PWV), augmentation pressure (AP), augmentation index (AIx) and heart rate normalized augmentation index (AIx@75) were used as parameters of arterial stiffness. Results: The two groups were compared according to demographic characteristics, medications currently being taken, and levels of serum lipids. There was no significant difference between the groups. AP in group I was significantly higher than that of group II (p0.002). AIx and AIx@75 were similar in both groups. Aortic PWV of group I was significantly higher than that of group II (p<0.0001). Conclusion: According to the results of this study, the presence of aortic calcification, verified by chest radiography, was associated with increased aortic PWV.
Açıklama
Anahtar Kelimeler
Kalp ve Kalp Damar Sistemi
Kaynak
Türk Kardiyoloji Derneği Arşivi
WoS Q Değeri
Scopus Q Değeri
Cilt
40
Sayı
8
