Efficacy of preoperative neutrophil-to-lymphocyte ratio in determining lymph node metastases in testicular cancer

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dc.contributor.authorKoseci, Tolga
dc.contributor.authorHaksoyler, Veysel
dc.contributor.authorKaradeniz, Cemile
dc.contributor.authorKaya, Dilsa Mizrak
dc.contributor.authorDilek, Okan
dc.contributor.authorSungur, Mehmet Ali
dc.contributor.authorCil, Timucin
dc.date.accessioned2021-12-01T18:50:13Z
dc.date.available2021-12-01T18:50:13Z
dc.date.issued2021
dc.department[Belirlenecek]en_US
dc.description.abstractPurpose: Testicular cancer is the most common solid tumor in young men between the ages of 20-35 and has excellent clinical outcomes with appropriate treatment. Neutrophil-to-lymphocyte-ratio (NLR) is related with prognosis and relapse in different solid tumors. We aimed to investigate the relation of presence and size of regional lymph node metastasis with NLR in testicular cancer. Materials and Methods: A total of 72 testicular cancer patients were included in the study. All medical records were retrospectively collected. NLR was calculated as the count of neutrophil divided by the count of lymphocyte. Chest and abdomen computed tomograpy (CT) scans of all patients were evaluated for metastases. Results: The mean age was 32.18 +/- 8.89 years. The pathologic classification was seminoma in 43% and nonseminoma in 57% of patients. Of 72 patients, 32 (44.4%) had lymph node positivity and 40 (55.6%) hadnot. The mean NLR value was 2.63 +/- 1.79 for all cohort. The mean NLR was significantly lower in patients with lymph node negative disease (for lymph node positive and negative disease 3.19 +/- 2.32 and 2.25 +/- 1.06, respectively.). In the ROC analysis, 2.5 was determined as the cut-off value for NLR to assess lymph node status. Conclusion NLR is a cheap and readily available index that can be used to determine lymph node metastases in testicular GCTs.en_US
dc.identifier.doi10.17826/cumj.909567
dc.identifier.endpage1076en_US
dc.identifier.issn2602-3032
dc.identifier.issn2602-3040
dc.identifier.issue3en_US
dc.identifier.startpage1070en_US
dc.identifier.urihttps://doi.org/10.17826/cumj.909567
dc.identifier.urihttps://hdl.handle.net/20.500.12684/10846
dc.identifier.volume46en_US
dc.identifier.wosWOS:000695272700024en_US
dc.identifier.wosqualityN/Aen_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.language.isoenen_US
dc.publisherCukurova Univ, Fac Medicineen_US
dc.relation.ispartofCukurova Medical Journalen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.subjectGerm cell tumoren_US
dc.subjecttesticular canceren_US
dc.subjectneutrophil lymphocyte ratioen_US
dc.subjectlymph node metastasesen_US
dc.subjectInflammationen_US
dc.titleEfficacy of preoperative neutrophil-to-lymphocyte ratio in determining lymph node metastases in testicular canceren_US
dc.typeArticleen_US

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