The role of inflammation in children with specific learning disorders

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dc.contributor.authorOz, Busra
dc.contributor.authorArdic, Berkan
dc.date.accessioned2024-08-23T16:03:29Z
dc.date.available2024-08-23T16:03:29Z
dc.date.issued2023en_US
dc.departmentDüzce Üniversitesien_US
dc.description.abstractBackground: Specific learning disorder (SLD) is a common neurodevelopmental disorder in childhood with a delay in reading, writing, and/or mathematics. The etiology of SLD is not known exactly. Aim: In our study, we aimed to evaluate the effect of inflammation in the etiology of SLD. Materials and Methods: In our study, patients aged 7-14 years who applied to the child psychiatry outpatient clinic between November 2019 and November 2020 were retrospectively screened. The hemoglobin (Hb), red cell distribution width (RDW), platelet (PLT), plateletcrit (PCT), platelet distribution width (PDW), and white blood cell (WBC) values of the children were recorded. Neutrophil/lymphocyte ratio (NLR) and PLR values were calculated. Comparisons were carried out on different variables using SPSS version 22. Results: There was no significant difference in terms of age and gender in the SLD and control groups. When blood parameters were evaluated, there was no significant difference between the groups in terms of Hb, RDW, PCT, PDW, and WBC values. The PLT count was significantly higher in the patient group than in the control group (P = 0.049). There was no significant difference between the groups in terms of TLR and NLR values. Conclusion: The results of our study showed that Hb, RDW, PCT, PDW, WBC, NLR, and TLR values were similar in SLD and healthy control groups. This does not support the hypothesis that an increased inflammatory response may be responsible for the etiology of SLD. Considering the heterogeneity in the clinical symptoms and etiopathogenesis of SLD, more extensive studies are needed in this area.en_US
dc.identifier.doi10.4103/aip.aip_129_22
dc.identifier.endpage102en_US
dc.identifier.issn2588-8358
dc.identifier.issn2588-8366
dc.identifier.issue2en_US
dc.identifier.startpage96en_US
dc.identifier.urihttps://doi.org/10.4103/aip.aip_129_22
dc.identifier.urihttps://hdl.handle.net/20.500.12684/13775
dc.identifier.volume7en_US
dc.identifier.wosWOS:001066573300003en_US
dc.identifier.wosqualityQ4en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.language.isoenen_US
dc.publisherWolters Kluwer Medknow Publicationsen_US
dc.relation.ispartofAnnals of Indian Psychiatryen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectInflammationen_US
dc.subjectlymphocyteen_US
dc.subjectneutrophilen_US
dc.subjectspecific learning disorderen_US
dc.subjectNeutrophil-Lymphocyte Ratioen_US
dc.subjectAdolescentsen_US
dc.subjectMarkersen_US
dc.titleThe role of inflammation in children with specific learning disordersen_US
dc.typeArticleen_US

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