Clinical Picture at Attendance and Response to Flexible Family-Based Low-Carb Life Style Change in Children With Obesity

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Tarih

2021

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Dergi ISSN

Cilt Başlığı

Yayıncı

Lifescience Global

Erişim Hakkı

info:eu-repo/semantics/openAccess

Özet

Aim: The study aims 1) to determine the clinical status of obese children at the admittance to the pediatric endocrinology referral center 2) to investigate the efficiency and compliance of the low-carb diet in a pediatric population with or without exercise, metformin Material and Methods: All subjects with the complaint of obesity and BMI percentile >95 were recruited from January 2012-August 2014. We evaluated basal retrospectively, recommended low carbohydrate family-wide eating practice and exercise to all, and metformin to selected cases, and recorded Self- reported adherence at first, third, sixth, and twelfth months. Results: Thirty-six subjects used metformin with a higher ratio of weight loss (90.0%, p=0.010) without a difference in the number of lost kilograms. In 160 cases without metformin; diet only, exercise only, and both diet and exercise groups lost weight significantly according to neither diet nor exercise group (OR:12.08, 95% CI 3.93-41.66, p<0.001; OR:3.04, 95% CI 1.18-7.84, p=0.022 and OR:32.80, 95% CI 7.14-150.77, p<0.001 respectively). Exercise plus diet (95.3%, p=0,002) and only diet (88.9%, p=0,023) were even more efficient than exercise alone (65.5%). In the twelfth month, 13.8% were on follow-up. Conclusion: Obesity gives rise to metabolic complications in the very early stages. A low carbohydrate diet proved to be acceptable and useful. Long-term consistency remains a challenge.

Açıklama

Anahtar Kelimeler

Children, Complications, Low-carbohydrate diet, Metformin, Obesity, Randomized Controlled-Trial, Insulin-Resistance, Glucose-Tolerance, Childhood Obesity, Pediatric Obesity, Low-Carbohydrate, Overweight, Management, Adolescents, Risk

Kaynak

International Journal Of Child Health And Nutrition

WoS Q DeÄŸeri

N/A

Scopus Q DeÄŸeri

Cilt

10

Sayı

1

Künye