Allele distribution data for 16 short tandem repeat loci in Bolu

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dc.contributor.authorTuğ, Ayşim
dc.contributor.authorErkol, Zerrin
dc.contributor.authorÇetinyürek, Aysun
dc.contributor.authorAlakoç, Yeşim Doğan
dc.contributor.authorElma, Cüneyt
dc.contributor.authorBüken, Bora
dc.contributor.authorErkol, Hayri
dc.date.accessioned2020-04-30T22:39:03Z
dc.date.available2020-04-30T22:39:03Z
dc.date.issued2010
dc.departmentDÜ, Tıp Fakültesi, Dahili Tıp Bilimleri Bölümüen_US
dc.descriptionDogan Alakoc, Yesim/0000-0001-6650-6133en_US
dc.descriptionWOS: 000281832100022en_US
dc.description.abstractAim: To examine the short tandem repeat (STR) data of Bolu population and compare the data with previously published population studies and with the data of a neighboring province, Duzce (a former district of Bolu), which became a province after the earthquake in 1999. Materials and methods: Blood samples were taken from 175 unrelated individuals. DNA was isolated using a DNA Kit and the amplification was performed using an AmpFeSTR Identifier kit. Genotyping was carried out by an ABI Prism 310 genetic analyzer by using a reference ladder. Several parameters, such as allele frequencies, Hardy-Weinberg equilibrium, power of exclusion, power of discrimination, pairwise comparison, were calculated and correction test was used to confirm significant differences found in the comparative analysis Results: According to their power of exclusion and power of discrimination values, the most discriminating loci were D18S51 and D2S1338 whereas TPOX appears to be the least The most discriminating loci and paternity index were found to be different in Bolu and its former district, Duzce, which is an interesting result. Conclusion: The results indicate the importance of local population studies, because in regions where migration occurs and marriages between members of different ethnic groups are not socially acceptable, genetic data are affected.en_US
dc.description.sponsorshipAbant Izzet Baysal University Scientific Research FoundationAbant Izzet Baysal Universityen_US
dc.description.sponsorshipThis research was supported by the Abant Izzet Baysal University Scientific Research Foundation.en_US
dc.identifier.doi10.3906/sag-0805-63en_US
dc.identifier.endpage664en_US
dc.identifier.issn1300-0144
dc.identifier.issn1303-6165
dc.identifier.issue4en_US
dc.identifier.startpage659en_US
dc.identifier.urihttps://doi.org/10.3906/sag-0805-63
dc.identifier.urihttps://hdl.handle.net/20.500.12684/2580
dc.identifier.volume40en_US
dc.identifier.wosWOS:000281832100022en_US
dc.identifier.wosqualityQ4en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.language.isoenen_US
dc.publisherTubitak Scientific & Technical Research Council Turkeyen_US
dc.relation.ispartofTurkish Journal Of Medical Sciencesen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectDNA analysisen_US
dc.subjectshort tandem repeatsen_US
dc.subjectpopulation geneticsen_US
dc.subjectBoluen_US
dc.subjectTurkeyen_US
dc.titleAllele distribution data for 16 short tandem repeat loci in Boluen_US
dc.typeArticleen_US

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