Comparison of Serum Lipid Levels in Chronic Obstructive Pulmonary Disease and Lung Cancer

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dc.contributor.authorKöş, Mehmet
dc.contributor.authorSoysal, Tuba
dc.contributor.authorAydın, Leyla
dc.contributor.authorTitiz, Hafize
dc.contributor.authorKöş, Fahriye Tuğba
dc.contributor.authorÜnlü, Nisa
dc.date.accessioned2020-04-30T22:41:25Z
dc.date.available2020-04-30T22:41:25Z
dc.date.issued2015
dc.departmentDÜ, Tıp Fakültesi, Dahili Tıp Bilimleri Bölümüen_US
dc.descriptionSoysal, Teoman/0000-0002-7417-2118;en_US
dc.descriptionWOS: 000215591800030en_US
dc.description.abstractAim: Relationship between serum lipid level in chronic obstructive lung disease (COLD) and lung cancer was not well documented. In our study we planned to compare serum lipid levels (Total Cholesterol-TC, low density lipoprotein cholesterol-LDL-C, trigliseride-TGL, and high density lipoprotein cholesterol-HDL-C) in these common diseases. Material and Method: We evaluated 100 patients and 50 control group retrospectively. We enrolled the lipid parameters before any medical treatment start. Student's t-test and one-way ANOVA test was used for comparison of the patient characteristics and mean cholesterol level. Results: TC levels were higher in COLD disease than lung cancer group but not statistically significant. TGL levels were higher in lung cancer group than COLD and control group but this was also not statistically significant. Mild-moderate degree COLD patients had lower HDL-C than severe COLD patients (p=0.02). But TC and TGL levels were lower in severe COLD pateints. Small cell lung sancer and non-small lung cancers had statistically significantly lower TC and TGL levels (respectively p=0.04 and p=0.02). Discussion: We estimated that lipid leves of at the beginning of COLD were decreased to provide lipid necessity in cancer tissue due to tumor rapid cell proliferation in cancer, tumor cachexia and increased nutrition problems when developed lung cancer. Larger prospective studies are required to more accurate assessment this issue.en_US
dc.identifier.doi10.4328/JCAM.3182en_US
dc.identifier.endpage382en_US
dc.identifier.issn1309-0720
dc.identifier.issn1309-2014
dc.identifier.startpage379en_US
dc.identifier.urihttps://doi.org/10.4328/JCAM.3182
dc.identifier.urihttps://hdl.handle.net/20.500.12684/3183
dc.identifier.volume6en_US
dc.identifier.wosqualityN/Aen_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.language.isotren_US
dc.publisherDerman Medical Publen_US
dc.relation.ispartofJournal Of Clinical And Analytical Medicineen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectLipid Levelsen_US
dc.subjectCOPDen_US
dc.subjectLung Canceren_US
dc.titleComparison of Serum Lipid Levels in Chronic Obstructive Pulmonary Disease and Lung Canceren_US
dc.typeArticleen_US

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