The effects of smoking on the placentas of smoker mothers in terms of MPO, MMP-9 and FGF

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dc.authoriderdem, havva/0000-0002-3074-0240
dc.authorwosiderdem, havva/E-9297-2015
dc.contributor.authorAslan, Ali
dc.contributor.authorKaratas, Ahmet
dc.contributor.authorErdem, Havva
dc.contributor.authorKadioglu, Nilufer
dc.contributor.authorAnkarali, Handan
dc.contributor.authorAdmis, Ozlem
dc.date.accessioned2021-12-01T18:50:32Z
dc.date.available2021-12-01T18:50:32Z
dc.date.issued2020
dc.department[Belirlenecek]en_US
dc.description6th World Congress of Oxidative Stress, Calcium Signaling and TRP Channels -- MAY 24-27, 2016 -- Isparta, TURKEYen_US
dc.description.abstractAim: Smoking during pregnancy remains a common habit. Pregnant smokers harm both themselves and their fetus. Therefore, in this study, we aimed to investigate oxidative stress and angiogenic effects of smoking on pregnant smokers by analyzing FGF, MMP-9, and MPO levels. Material and Methods: The placentas of 68 pregnant women which referred to the pathology laboratory between the years 2010 and 2011 were included in the study. Of the total, 28 women were smokers (S) and 40 women were non-smokers (NS). The FGF, MMP-9, and MPO immunostaining of placental tissues were examined by manual microarray study. The number of cigarettes smoked, age, systemic disease rate, mean abortus number, blood pressure, hemoglobin and hematocrit, Apgar, and pathological parameters were also evaluated. Results: Statistically significant positive relationships were found between S and NS groups in terms of MMP-9 staining (grade 1) (p=0.039). There was no MMP-9 staining in S group. Systemic diseases were more frequent in S than NS group (p=0.049). There was no statistically significant relationship between other parameters. Discussion: The effects of smoking on the fetus have been demonstrated with MMP-9. More comprehensive studies are needed to reveal the relationship between fetus and smoking.en_US
dc.identifier.doi10.4328/ACAM.20123
dc.identifier.endpage46en_US
dc.identifier.issn2667-663X
dc.identifier.startpage42en_US
dc.identifier.urihttps://doi.org/10.4328/ACAM.20123
dc.identifier.urihttps://hdl.handle.net/20.500.12684/10892
dc.identifier.volume11en_US
dc.identifier.wosWOS:000572739500012en_US
dc.identifier.wosqualityN/Aen_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.language.isoenen_US
dc.publisherBayrakol Medical Publisheren_US
dc.relation.ispartofAnnals Of Clinical And Analytical Medicineen_US
dc.relation.publicationcategoryKonferans Öğesi - Uluslararası - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.subjectSmokingen_US
dc.subjectFGFen_US
dc.subjectMMP-9en_US
dc.subjectMPOen_US
dc.subjectPlacentaen_US
dc.subjectExpressionen_US
dc.subjectAngiogenesisen_US
dc.subjectFetalen_US
dc.titleThe effects of smoking on the placentas of smoker mothers in terms of MPO, MMP-9 and FGFen_US
dc.typeConference Objecten_US

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