Levels of paraoxonase, high-density lipoprotein and total sialic acid levels in patients with polycystic ovary syndrome

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dc.contributor.authorDeveci, Haci Ahmet
dc.contributor.authorNur, Gökhan
dc.contributor.authorAlpay, Merve
dc.contributor.authorÖzmerdivenli, Recep
dc.date.accessioned2025-03-24T19:48:33Z
dc.date.available2025-03-24T19:48:33Z
dc.date.issued2017
dc.departmentDüzce Üniversitesi
dc.description.abstractParaoxonase (PON1) have been considered to have a role in various pathological processes, including inflammatory response, cardiovascular disease and recently also in ovarian dysfunction. We aimed to evaluate relation high density lipoprotein cholesterol (HDL) levels and PON1 activity and total sialic acid status (TSA) levels in serum of patients with polycystic ovary syndrome (PCOS) and healthy individuals. Twenty PCOS patients (PCOS group) and 20 healthy nonhyperandrogenic women (control group) were studied in the current study. Levels of HDL, TSA, and activity of PON1 were measured in serum of PCOS patients. Levels of PON1 activity and level of HDL were significantly lower in the PCOS group than in the control group. TSA levels were higher in the PCOS group than the control group. There was also a significant correlation between the parameters and syndrome initiation. In conclusion, patients with PCOS had high level of PON1. It might be hypothesized that elevated serum TSA, HDL and PON1 may be associated with increased cardiovascular risk in PCOS and/or menstrual irregularities associated with this syndrome.
dc.identifier.doi10.37212/jcnos.333052
dc.identifier.endpage636
dc.identifier.issn2149-7222
dc.identifier.issue2
dc.identifier.startpage630
dc.identifier.urihttps://doi.org/10.37212/jcnos.333052
dc.identifier.urihttps://hdl.handle.net/20.500.12684/19034
dc.identifier.volume9
dc.language.isoen
dc.publisherHücresel Sinir Bilimleri ve Oksidatif Stres Derneği
dc.relation.ispartofJournal of Cellular Neuroscience and Oxidative Stress
dc.relation.publicationcategoryMakale - Ulusal Hakemli Dergi - Kurum Öğretim Elemanı
dc.rightsinfo:eu-repo/semantics/openAccess
dc.snmzKA_DergiPark_20250324
dc.subjectpolycystic ovary syndrome|Paraoxonase|total sialic acid|high density lipoprotein|follicle stimulating hormone|reactive nitrogen species
dc.titleLevels of paraoxonase, high-density lipoprotein and total sialic acid levels in patients with polycystic ovary syndrome
dc.typeArticle

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