Yoğun Bakım Ünitemizde Candida Skoru ve Candida Kolonizasyon İndeksi'nin Kandidemi İnsidansındaki Azalmaya Etkisinin Karşılaştırılması

Basit Öğe Kaydı
dc.contributor.authorPekok, Abdullah Umut
dc.contributor.authorYabalak, Ahmet
dc.contributor.authorÖzkan, Sedef Tavukçu
dc.contributor.authorKement, Metin
dc.contributor.authorPekok, Mehmet
dc.contributor.authorPekok, Berfin Sude
dc.date.accessioned2025-03-24T19:47:15Z
dc.date.available2025-03-24T19:47:15Z
dc.date.issued2024
dc.departmentDüzce Üniversitesi
dc.description.abstractAim: Since candidemia is an important cause of mortality and morbidity in hospitals, especially in intensive care units (ICU), those hospitalized in the ICU; In patients with risk factors such as invasive device use and undergoing abdominal surgery, early empirical antifungal therapy is recommended to reduce mortality according to the results of candida score (CS) and candida colonization index (CCI). In this study, the data of the patients who were followed up in the ICU, who were started on empirical treatment according to KS and CCI, were evaluated and their effects on the incidence of candidemia were analyzed. Method: Cultures taken from 100 patients hospitalized in the intensive care unit where adult patients were followed between 01.06.2018 and 01.08.2021 were examined. While investigating the colonization index of each patient, swab samples were taken once during the hospitalization from five main sites: mouth, nose, skin, perineum, and catheter. Samples taken with sterile swabs were inoculated on Sabouraud dextrose agar (SDA) plates and the plates were incubated at 35°C for 48 hours. The yeast colonies formed were defined according to their microscopic appearance and biochemical properties. CCI and CS of the patients were evaluated and fluconazole prophylaxis was started in patients with KS ?3 or CCI ?0.5. Results: A total of 500 culture samples from 100 non-neutropenic adult patients were analyzed (Mean of 5 cultures/patient). No growth was detected in any of the samples in 32 (32 %) of 100 patients, and growth was detected in at least one of the samples taken from 68 patients (68 %). Reproduction was detected from a total of 118 samples. Of the yeasts, 104 were identified as Candida albicans, 10 as Candida glabrata and 4 as Candida inconspicua. CS? 3 and CCI ?0.5 in 11 (11%) patients, and CS?3, CCI
dc.description.abstractAim: Since candidemia is an important cause of mortality and morbidity in hospitals, especially in intensive care units (ICU), those hospitalized in the ICU; In patients with risk factors such as invasive device use and undergoing abdominal surgery, early empirical antifungal therapy is recommended to reduce mortality according to the results of candida score (CS) and candida colonization index (CCI). In this study, the data of the patients who were followed up in the ICU, who were started on empirical treatment according to KS and CCI, were evaluated and their effects on the incidence of candidemia were analyzed. Method: Cultures taken from 100 patients hospitalized in the intensive care unit where adult patients were followed between 01.06.2018 and 01.08.2021 were examined. While investigating the colonization index of each patient, swab samples were taken once during the hospitalization from five main sites: mouth, nose, skin, perineum, and catheter. Samples taken with sterile swabs were inoculated on Sabouraud dextrose agar (SDA) plates and the plates were incubated at 35°C for 48 hours. The yeast colonies formed were defined according to their microscopic appearance and biochemical properties. CCI and CS of the patients were evaluated and fluconazole prophylaxis was started in patients with KS ?3 or CCI ?0.5. Results: A total of 500 culture samples from 100 non-neutropenic adult patients were analyzed (Mean of 5 cultures/patient). No growth was detected in any of the samples in 32 (32 %) of 100 patients, and growth was detected in at least one of the samples taken from 68 patients (68 %). Reproduction was detected from a total of 118 samples. Of the yeasts, 104 were identified as Candida albicans, 10 as Candida glabrata and 4 as Candida inconspicua. CS? 3 and CCI ?0.5 in 11 (11%) patients, and CS?3, CCI
dc.identifier.doi10.19161/etd.1301169
dc.identifier.endpage389
dc.identifier.issn1016-9113
dc.identifier.issn2147-6500
dc.identifier.issue3
dc.identifier.startpage383
dc.identifier.urihttps://doi.org/10.19161/etd.1301169
dc.identifier.urihttps://hdl.handle.net/20.500.12684/18597
dc.identifier.volume63
dc.language.isoen
dc.publisherEge University
dc.relation.ispartofEge Tıp Dergisi
dc.relation.publicationcategoryMakale - Ulusal Hakemli Dergi - Kurum Öğretim Elemanı
dc.rightsinfo:eu-repo/semantics/openAccess
dc.snmzKA_DergiPark_20250324
dc.subjectKandida kolonizasyon indeksi|kandida skoru|kandidemi insidansı|anti-fungal profilaksi|Candida colonization index|candida score|incidence of candidemia|anti-fungal prophylaxis
dc.titleYoğun Bakım Ünitemizde Candida Skoru ve Candida Kolonizasyon İndeksi'nin Kandidemi İnsidansındaki Azalmaya Etkisinin Karşılaştırılması
dc.title.alternativeComparison of The Effect of Candida Score and Candida Colonization Index on Decrease in Candidemia Incidence in Our Intensive Care Unit
dc.typeArticle

Dosyalar

Koleksiyon

Öksüz Yayınlar Koleksiyonu