Determination of taxanes by validated LC-MS/MS method in hazelnut collected from different regions and altitudes in Turkey

Basit Öğe Kaydı
dc.contributor.authorOğuzkan, Sibel Bayıl
dc.contributor.authorKaragül, Bora
dc.contributor.authorAksoy, Elif Sine
dc.contributor.authorUzun, Ayşe
dc.contributor.authorCan, Merve
dc.contributor.authorYılmaz, Hasibe
dc.contributor.authorGören, Ahmet C.
dc.date.accessioned2020-05-01T09:11:21Z
dc.date.available2020-05-01T09:11:21Z
dc.date.issued2018
dc.departmentDÜ, Fen-Edebiyat Fakültesi, Kimya Bölümüen_US
dc.descriptionoguzkan, sibel Bayil/0000-0003-0254-6915; Goren, Ahmet C/0000-0002-5470-130Xen_US
dc.descriptionWOS: 000436246200003en_US
dc.description.abstractIn this study, mass fractions of paclitaxel, cephalomannine, 10-DAB III and baccatin III in hazelnut were measured with new and validated LC-MS/MS method. Green outer nut husk and nutshell of Turkish hazelnut (Corylus colurna L.) were collected from Duzce, Trabzon, Adapazari and Samsun at several altitudes during August and September in 2014. The target analytes were prepared using solid-liquid extraction and analysed by LC-MS/MS. High amount of baccatin III, used for synthesizing semi-synthetic paclitaxel, was found in the nutshells collected at 250-500 m altitude in Cumayeri district of Duzce. In the husk samples from Vakfikebir district of Trabzon, the highest amount of baccatin III was obtained. The mass fractions of baccatin III in nutshell and husks were between 164.38-1020.85 mu gkg-1 and 166.12-923.64 mu gkg-1, respectively.en_US
dc.description.sponsorshipScientific and Technological Research Council of Turkey (TUBITAK)Turkiye Bilimsel ve Teknolojik Arastirma Kurumu (TUBITAK) [114Z233]en_US
dc.description.sponsorshipThis study is supported by a grant (Project Number:114Z233) from Scientific and Technological Research Council of Turkey (TUBITAK)en_US
dc.identifier.doi10.25135/jcm.16.18.03.082en_US
dc.identifier.endpage33en_US
dc.identifier.issn1307-6183
dc.identifier.issue1en_US
dc.identifier.startpage26en_US
dc.identifier.urihttps://doi.org/10.25135/jcm.16.18.03.082
dc.identifier.urihttps://hdl.handle.net/20.500.12684/5529
dc.identifier.volume12en_US
dc.identifier.wosqualityN/Aen_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.language.isoenen_US
dc.publisherAcg Publicationsen_US
dc.relation.ispartofJournal Of Chemical Metrologyen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.subjectTaxanesen_US
dc.subjectbaccatin IIIen_US
dc.subjecthazelnuten_US
dc.subjectLC-MS/MSen_US
dc.subjectmethod validationen_US
dc.titleDetermination of taxanes by validated LC-MS/MS method in hazelnut collected from different regions and altitudes in Turkeyen_US
dc.typeArticleen_US

Dosyalar

Orijinal paket
Listeleniyor 1 - 1 / 1
Küçük Resim
İsim:
5529.pdf
Boyut:
7.29 MB
Biçim:
Adobe Portable Document Format
Açıklama:
Tam Metin / Full Text
İndir

Koleksiyon

WoS İndeksli Yayınlar Koleksiyonu
Makale Koleksiyonu