The role of FDG PET/CT in detection of distant metastasis in theinitial staging of breast cancer

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dc.contributor.authorAliyev, Anar
dc.contributor.authorAksoy, Sabire Yılmaz
dc.contributor.authorÖzhan, Meftune
dc.contributor.authorEkmekçioğlu, Özgül
dc.contributor.authorVatankulu, Betül
dc.contributor.authorKocael, Pınar Çiğdem
dc.contributor.authorHalaç, Metin
dc.date.accessioned2020-04-30T14:39:12Z
dc.date.available2020-04-30T14:39:12Z
dc.date.issued2016
dc.departmentDÜ, Tıp Fakültesi, Dahili Tıp Bilimleri Bölümüen_US
dc.description.abstractBackground/aim: We aimed to evaluate the role of FDG PET/CT in the detection of extraaxillary regional nodal/distant metastasis in breast cancer patients and to assess the value of FDG PET/CT for detecting distant metastases in patient subgroups. Materials and methods: A total of 254 patients with breast cancer (248 female, 6 male) who underwent PET/CT for initial staging were enrolled. Patients were divided into four groups: Group 1 consisted of 154 patients diagnosed by tru-cut/core/FNAB, Group 2 comprised 32 patients diagnosed by excisional biopsy, Group 3 included 62 patients who had mastectomy-axillary lymph node dissection, and Group 4 consisted of 6 patients who had axillary lymph node metastasis diagnosed by excisional biopsy. Results: PET/CT detected distant metastasis in 76 of the 254 patients. Of these patients, 21.7% had bone/bone marrow metastasis, 7.1% had lung metastasis, 13% had mediastinal lymph node metastasis, 4.8% had liver metastasis, 9.8% had other organ/system metastasis, and 6% had other lymphadenopathies. According to T staging, the percentages of distant metastasis were as follows: 13.6% of the 66 T1 stage patients, 35.7% of the 129 T2 stage patients, 40% of the 20 T3 stage patients, and 33.3% of the 39 T4 stage patients. Conclusion: FDG-PET/CT led to a change in the stage of disease and the treatment approach in newly diagnosed breast cancer patients due to its superiority in detecting extraaxillary regional lymph node metastases and distant metastases.en_US
dc.identifier.endpage360en_US
dc.identifier.issn1300-0144
dc.identifier.issn1303-6165
dc.identifier.issue2en_US
dc.identifier.startpage349en_US
dc.identifier.urihttps://app.trdizin.gov.tr/makale/TWpRNE1ETXdNQT09
dc.identifier.urihttps://hdl.handle.net/20.500.12684/1318
dc.identifier.volume46en_US
dc.indekslendigikaynakTR-Dizinen_US
dc.language.isoenen_US
dc.relation.publicationcategoryMakale - Ulusal Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.subjectCerrahien_US
dc.titleThe role of FDG PET/CT in detection of distant metastasis in theinitial staging of breast canceren_US
dc.typeArticleen_US

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