First Report on Bio-accessibility, Anti-oxidant Activity and Total Phenolic Compounds From Stachys thirkei C. Koch Using A Simulated In Vitro Digestion System

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dc.contributor.authorDülger, Görkem
dc.contributor.authorRasgele, Pınar Göç
dc.contributor.authorAydın, Emine
dc.date.accessioned2023-07-26T11:54:58Z
dc.date.available2023-07-26T11:54:58Z
dc.date.issued2022
dc.departmentDÜ, Ziraat Fakültesi, Tarımsal Biyoteknoloji Bölümüen_US
dc.description.abstractIt is of great importance to detect the anti-oxidant features of plants, particularly those used for food, pharmacology and medicinal purposes. Stachys thirkei C. Koch belonging to Lamiaceae family is utilised as a medicinal aromatic plant in Turkey. It was aimed to investigate the total phenolic content (TPC), anti-oxidant activity and bio-accessibility of S. thirkei C. Koch. The TPC was evaluated by Folin-Ciocalteu colorimetric proce-dure and antioxidant activity to determine four distinctive assays (ABTS•+, CUPRAC, DPPH• and FRAP). The experimental analysis showed that, the levels of hydrolysable phenolics (1538.99 mg of GAE/100g) approximately three and a half fold higher than extractable phenolics (422.96 mg of GAE/100g). The TPC of S. thirkei C. Koch was determined to be 1961.95 mg of GAE/100g. Moreover, the bio-accessible fractions and phenolic bio-accessibility of S. thirkei C. Koch were found to be 1766.72 ?mol Trolox/g and 90.05 %, respectively. At the same time, the antioxidative bio-accessibility of S. thirkei C. Koch was found to be higher in FRAP method (1164.29 ?mol Trolox/g) and also the bio-accessibility (%) of S. thirkei C. Koch was found to be higher in CUPRAC method (93.41%). Present investigation is the primary report to investigate the bio-accessibility of the extracts from S. thirkei C. Koch. The results of the present may be strong scientific evidence to use S. thirkei C. Koch as a favorable source of antioxidant and the researches can be further extended to investigate whether they exhibit similar activities in in vivo systems.en_US
dc.identifier.doi10.28979/jarnas.1014968
dc.identifier.endpage200en_US
dc.identifier.issn2757-5195
dc.identifier.issue2en_US
dc.identifier.startpage188en_US
dc.identifier.trdizinid1120791en_US
dc.identifier.urihttp://doi.org/10.28979/jarnas.1014968
dc.identifier.urihttps://search.trdizin.gov.tr/yayin/detay/1120791
dc.identifier.urihttps://hdl.handle.net/20.500.12684/12968
dc.identifier.volume8en_US
dc.indekslendigikaynakTR-Dizinen_US
dc.institutionauthorAydın, Emine
dc.language.isoenen_US
dc.relation.ispartofJournal of advanced research in natural and applied sciences (Online)en_US
dc.relation.publicationcategoryMakale - Ulusal Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.snmz$2023V1Guncelleme$en_US
dc.titleFirst Report on Bio-accessibility, Anti-oxidant Activity and Total Phenolic Compounds From Stachys thirkei C. Koch Using A Simulated In Vitro Digestion Systemen_US
dc.typeArticleen_US

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