Electroencephalogram Abnormalities and Epilepsy in Autism Spectrum Disorders: Clinical and Electroencephalogram Findings

dc.authoridTuray, Sevim/0000-0001-6002-052X
dc.contributor.authorHanci, Fatma
dc.contributor.authorTuray, Sevim
dc.contributor.authorOzturk, Yusuf
dc.contributor.authorKabakus, Nimet
dc.date.accessioned2021-12-01T18:48:09Z
dc.date.available2021-12-01T18:48:09Z
dc.date.issued2021
dc.department[Belirlenecek]en_US
dc.description.abstractIt has been known for several decades that epilepsy and autism spectrum disorders (ASD) are related to each other. Epilepsy frequently accompanies ASD. The purpose of this study was to investigate relationship between clinical and electroencephalogram (EEG) findings in ASD patients and to identify EEG characteristics that may create a disposition to epilepsy in ASD by examining differences in clinical and EEG findings between patients diagnosed with ASD without epilepsy and ASD with epilepsy. A total of 102 patients aged 2 to 18 years and diagnosed with ASD based on Diagnostic and Statistical Manual of Mental Disorders, fifth edition (DSM-5) diagnostic criteria between January 2017 and June 2019 were included in the study. Patients were assigned into two groups: (1) ASD with epilepsy and (2) ASD without epilepsy. Clinical findings were retrieved from patients' files, and EEG findings from first EEG records in the EEG laboratory at the time of diagnosis. EEG findings were defined as central, parietal, frontal, temporal, or generalized, depending on the location of rhythmic discharges. The incidence of epilepsy in our ASD patients was 33.7% and that of febrile convulsion was 4%. Generalized motor seizures were the most common seizure type. Epileptic discharges most commonly derived from the central and frontal regions. These abnormalities, especially frontal and central rhythmic discharges, may represent a precursor for the development of epilepsy in ASD patients.en_US
dc.identifier.doi10.1055/s-0041-1736557
dc.identifier.issn2146-457X
dc.identifier.issn2146-4588
dc.identifier.urihttps://doi.org/10.1055/s-0041-1736557
dc.identifier.urihttps://hdl.handle.net/20.500.12684/10469
dc.identifier.wosWOS:000712592100001en_US
dc.identifier.wosqualityN/Aen_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.language.isoenen_US
dc.publisherGeorg Thieme Verlag Kgen_US
dc.relation.ispartofJournal Of Pediatric Epilepsyen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectautism spectrum disordersen_US
dc.subjectelectroence-phalographyen_US
dc.subjectepilepsyen_US
dc.subjectEeg Abnormalitiesen_US
dc.subjectChildhooden_US
dc.titleElectroencephalogram Abnormalities and Epilepsy in Autism Spectrum Disorders: Clinical and Electroencephalogram Findingsen_US
dc.typeArticleen_US

Dosyalar