Neonatal Graves' disease occurring in an infant whose mother had a thyroidectomy due to Graves' disease [Graves hastali?i nedeniyle tiroidektomi olan annenin yenido?an bebe?inde Graves hastali?i: Bir vaka takdimi]
Küçük Resim Yok
Tarih
2015
Dergi Başlığı
Dergi ISSN
Cilt Başlığı
Yayıncı
Cocuk Sagligi ve Hastaliklan Dergisi
Erişim Hakkı
info:eu-repo/semantics/closedAccess
Özet
Neonatal Graves' disease caused by fetal thyroid gland stimulation is the result of transplacental passage of maternal thyroid-stimulating hormone receptor antibodies in the second trimester of pregnancy. A mother with Graves-Basedow disease had a total thyroidectomy operation three months before a pregnancy; maternal TSH receptor antibody (TRAb) were detected at the sixth month of pregnancy. Antithyroid drug therapy was started to the 34 weeks' gestational age infant, who was diagnosed with neonatal hyperthyroidism. The condition improved after five weeks of antithyroid therapy. The pathogenesis was believed to be due to transplacental passage of maternal TRAb. This case is presented to highlight the fact that even mothers who have a total throidectomy for Graves' disease may have infants with rarely seen neonatal Graves' disease due to the presence of maternal TRAb in the circulation.
Açıklama
Anahtar Kelimeler
Graves' disease; Hyperthyroidism; Mother; Newborn; Total thyroidectomy; TSH receptor antibody
Kaynak
Cocuk Sagligi ve Hastaliklari Dergisi
WoS Q Değeri
Scopus Q Değeri
Q4
Cilt
58
Sayı
3
